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Usage

Uses

Used in Industrial Applications:
Sorbohydroxamic acid is used as a chelating agent for metal separation and extraction processes due to its strong complexation properties with a variety of metal ions, enhancing the efficiency of these processes.
Used in Pharmaceutical Research:
Sorbohydroxamic acid is being studied as a potential treatment for various forms of cancer. Its ability to bind to metal ions and inhibit certain enzymatic processes makes it a promising candidate for further research and development in the pharmaceutical industry. This application is based on its potential to target and disrupt metal-dependent biological pathways in cancer cells, thereby exhibiting anticancer activity.

InChI:InChI=1/C6H9NO2/c1-2-3-4-5-6(8)7-9/h2-5,9H,1H3,(H,7,8)/b3-2+,5-4+

Upstream product

• 110-44-1 sorbic Acid 

Relevant academic research and scientific papers

Synthesis of hydroxamic acids by activation of carboxylic acids with N,N'-carbonyldiimidazole: Exploring the efficiency of the method

Activation of carboxylic acids with N,N'-carbonyldiimidazole followed by the reaction with anhydrous or aqueous hydroxylamine hydrochloride was demonstrated to be an operationally simple method for the synthesis of hydroxamic acids in good yield and high purity after aqueous workup. The potential by-product, N,O-diacylhydroxylamine, is cleanly transformed to hydroxamic acid in these reaction conditions.

An expeditious hydroxyamidation of carboxylic acids

Capitalizing on in situ activation with the cyclic phosphonic anhydride PPAA (1), the conversion of carboxylic acids into hydroxamic acids has been reduced to an experimentally simple one-pot operation that addresses the issue of polyacylation without resorting to a large excess of hydroxylamine or to protection. Scope and selectivity were satisfactory with a wide range of substrates, including α,β-unsaturated acids and hydroxyacids.