407627-38-7Relevant academic research and scientific papers
Novel synthesis of 1,2,4-triazolo[4,3-a]pyrimidin-5-one derivatives
Hassaneen, Hamdi M,Abdelhadi, Hyam A,Abdallah, Tayseer A
, p. 10133 - 10138 (2007/10/03)
1,2-Dihydro-2-thioxopyrimidin-4(3H)ones 6 react with C-ethoxycarbonyl-N-arylhydrazonoyl chlorides 1 to give 1,2,4-triazolo[4,3-a]pyrimidines 11 in good yield. The latter products 11 react with benzenediazonium chloride, nitrous acid, acetyl chloride and chloroacetyl chloride to give the corresponding substitution products 16-18. The structures of the newly synthesized compounds are established on the basis of chemical and spectroscopic evidence.
