40775-79-9 Usage
General Description
2-Amino-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-ol, also known as Alovudine, is a chemical compound with a pyrimidine base structure. It is a nucleoside reverse transcriptase inhibitor (NRTI) that has shown antiviral activity against HIV and other retroviruses. Alovudine has been studied for its potential use in the treatment of HIV/AIDS and has shown promising results in preclinical studies. However, its development has been discontinued due to safety concerns, particularly its association with mitochondrial toxicity and lactic acidosis. Nonetheless, the unique structure of this compound makes it of interest for further research into potential antiviral drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 40775-79-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,7,7 and 5 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 40775-79:
(7*4)+(6*0)+(5*7)+(4*7)+(3*5)+(2*7)+(1*9)=129
129 % 10 = 9
So 40775-79-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H7N5O/c1-3-2-4(12)11-6(8-3)9-5(7)10-11/h2H,1H3,(H3,7,8,9,10)
40775-79-9Relevant articles and documents
SUBSTITUTED TRIAZOLO BICYCLICCOMPOUNDS AS PDE2 INHIBITORS
-
Page/Page column 181, (2017/01/23)
The present invention is directed to substituted triazolo bicycliccompounds of formula (I) which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 2 (PDE2). The present invention also
