4078-95-9Relevant academic research and scientific papers
An efficient synthesis of N-substituted phthalimides using SiO2-tpy-Nb as heterogeneous and reusable catalyst
Wan, Li,Sun, Xiaoning,Shi, Songjie,Zhang, Jiawei,Li, Xin,Li, Zhenjiang,Guo, Kai
, p. 30 - 34 (2017)
A novel and efficient heterogeneous catalyst SiO2-tpy-Nb was developed, and its application in the preparation of N-substituted phthalimides from o-phthalic acids or anhydrides with amines provides the desired products in good to excellent yields. The catalyst was stable and recoverable for eight consecutive cycles without a significant loss in its activity. Furthermore, the catalyst is applicable in continuous flow which indicates its potential utilization in industrialization.
