40801-12-5Relevant academic research and scientific papers
Synthesis of Polysubstituted Pyrroles through Electro-Oxidative Annulation of 1,3-Dicarbonyl Compounds and Primary Amines
Xiong, Mingteng,Liang, Xiao,Zhou, Yifeng,Pan, Yuanjiang
, p. 4986 - 4993 (2021)
Reported herein is a synthetic method of polysubstituted pyrroles from easily available materials, 1,3-dicarbonyl compounds and primary amines, via electro-oxidative intermolecular annulation. Under similar conditions, enamines are also converted smoothly into desired products, indicating that in situ formed enamines are crucial intermediates for the first transformation. Neither transition-metal salts nor harsh conditions are required to facilitate the dehydrocyclization process.
Synthesis of polysubstituted pyrroles via phi(OAC)2-mediated oxidative coupling of enamine esters and ketones
Wang, Jun-Yan,Liu, Su-Ping,Yu, Wei
experimental part, p. 2529 - 2533 (2010/02/28)
Enamine esters or ketones could undergo homocoupling by the action of (diacetoxyiodo)benzene in the presence of BF3OEt2, giving rise to pyrrole products. This reaction could be used to synthesize symmetric polysubstituted pyrroles. Some asymmetric polysub
The synthesis of polysubstituted pyrroles via the coupling of phenyliodonium ylides and enamine esters
Wang, Jun-Yan,Wang, Xian-Pei,Yu, Zheng-Sen,Yu, Wei
supporting information; experimental part, p. 2063 - 2066 (2009/12/29)
The boron trifluoride etherate (BF--Et2O)-catalyzed reactions between phenyliodonium ylides and enamine esters provide an efficient method for the synthesis of polysubstituted pyrroles.
