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(S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 40829-21-8 Structure
  • Basic information

    1. Product Name: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide
    2. Synonyms: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide
    3. CAS NO:40829-21-8
    4. Molecular Formula:
    5. Molecular Weight: 270.331
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 40829-21-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide(CAS DataBase Reference)
    10. NIST Chemistry Reference: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide(40829-21-8)
    11. EPA Substance Registry System: (S)-2-amino-N-benzyl-3-(4-hydroxyphenyl)propanamide(40829-21-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 40829-21-8(Hazardous Substances Data)

40829-21-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 40829-21-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,8,2 and 9 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 40829-21:
(7*4)+(6*0)+(5*8)+(4*2)+(3*9)+(2*2)+(1*1)=108
108 % 10 = 8
So 40829-21-8 is a valid CAS Registry Number.

40829-21-8Relevant articles and documents

Pd-Catalysed oxidative carbonylation of α-amino amides to hydantoins under mild conditions

Botla, Vinayak,Carfagna, Carla,Della Ca, Nicola,Gabriele, Bartolo,Maestri, Giovanni,Mancuso, Raffaella,Montanari, Luca,Motti, Elena,Voronov, Aleksandr

supporting information, p. 294 - 297 (2022/01/06)

The first example of palladium-catalysed oxidative carbonylation of unprotected α-amino amides to hydantoins is described here. The selective synthesis of the target compounds was achieved under mild conditions (1 atm of CO), without ligands and bases. The catalytic system overrode the common reaction pathway that usually leads instead to the formation of symmetrical ureas.

Protecting-Group-Free Amidation of Amino Acids using Lewis Acid Catalysts

Sabatini, Marco T.,Karaluka, Valerija,Lanigan, Rachel M.,Boulton, Lee T.,Badland, Matthew,Sheppard, Tom D.

supporting information, p. 7033 - 7043 (2018/05/04)

Amidation of unprotected amino acids has been investigated using a variety of ‘classical“ coupling reagents, stoichiometric or catalytic group(IV) metal salts, and boron Lewis acids. The scope of the reaction was explored through the attempted synthesis of amides derived from twenty natural, and several unnatural, amino acids, as well as a wide selection of primary and secondary amines. The study also examines the synthesis of medicinally relevant compounds, and the scalability of this direct amidation approach. Finally, we provide insight into the chemoselectivity observed in these reactions.

Histone deacetylase inhibitors: Synthesis of tetrapeptide analogue saha/tpx

Ekou, Lynda,Ekou, Tchirioua,Opalinski, Isabelle,Gesson, Jean Pierre

, p. S79-S84 (2012/06/15)

The inhibition of HDAC (histone deacetylase) activity by specific inhibitors induces growth arrest, differentiation and apoptosis of transformed or everal cancer cells. Some of these inhibitors are in clinical trial at phase I orphase II. The discovery an

Development of Potent Inhibitors of Botulinum Neurotoxin Type B

Anne, Christine,Turcaud, Serge,Quancard, Jean,Teffo, Franck,Meudal, Hervé,Fournié-Zaluski, Marie-Claude,Roques, Bernard P.

, p. 4648 - 4656 (2007/10/03)

Botulinum neurotoxins are the most potent toxins known to date. They are zinc-metalloproteases able to cleave selectively an essential component of neurotransmitter exocytosis, causing the syndrome of botulism characterized by a flaccid paralysis. There is a great interest in designing antagonists of the action of these toxins. One way is to inhibit their catalytic activity. In this study, we report the design of such inhibitors directed toward BoNT/B. A study of the S1 subsite specificity, using several β-amino thiols, has shown that this subsite prefers a p-carboxybenzyl moiety. The specificity of the S1′ and S2′ subsites was studied using two libraries of pseudotripeptides containing the S1 synthon derived from the best β-amino thiol tested. Finally, a selection of various non natural amino acids for the recognition of the "prime" domain led to the most potent inhibitor of BoNT/B described to date with a Ki value of 20 nM.

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