408318-32-1Relevant academic research and scientific papers
The Effect of the Structure of Substartes and Reaction Conditions on the Preparation of Acetylene 1,4-diols. II. Two-stage Syntheses
Olejnik, Marian,Jasiobedzki, Wieslaw,Pograniczna-Ramza, Maryla
, p. 467 - 473 (2007/10/02)
Twelve reactions of the preparation of asymmetric acetylene 1,4-diols have been carried out (Scheme I).A significant effect of the structure of initial ketone and the reaction conditions on the preparation of diols has been found in the first stage of the synthesis (prepartion of acetylene carbinol).For R1 or R2 = p-CH3OC6H4 products of dehydration of the dils have been obtained.
