408340-16-9

Usage

Structure

A phenol derivative with two iodine atoms attached to the 2 and 3 positions on the aromatic ring

Usage

As a precursor in the synthesis of various organic compounds, including pharmaceuticals, dyes, and pesticides

Properties

Strong oxidative properties, often used as a reagent for oxidation reactions in organic synthesis

Safety precautions

May be harmful if ingested, inhaled, or comes into contact with the skin or eyes, should be handled with caution.

Upstream product

• 626-02-8 3-Iodophenol 
• 863870-73-9 O-3-iodophenyl N,N-diethylcarbamate 
• 863870-82-0 O-2,3-diiodophenyl N,N-diethylcarbamate 

Downstream Products

• 1245635-31-7 t-butyl(2,3-diiodophenoxy)dimethylsilane 
• 1380450-03-2 4,4'-((3-(2-bromoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis(methoxybenzene) 
• 1380450-12-3 (E)-5-(4-fluorobenzylidene)-4-(4-fluorophenyl)-3,5-dihydro-2H-cyclopenta[de]chromene 
• 1380450-07-6 4,4'-((3-(2-iodoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis(fluorobenzene) 
• 1380450-08-7 2-(4-fluorophenyl)-4-((4-fluorophenyl)ethynyl)benzofuran 
• 1380450-09-8 2,3-bis((4-fluorophenyl)ethynyl)phenol 
• 1380450-16-7 2,2'-((3-(2-bromoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis((p-tolylethynyl)benzene) 
• 1380450-17-8 2,2'-((3-(2-bromoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis((phenylethynyl)benzene) 
• 1380450-18-9 2,2'-((3-(2-bromoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis(((4-methoxyphenyl)ethynyl)benzene) 
• 1380450-19-0 2,2'-((3-(2-iodoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis((p-tolylethynyl)benzene) 
• 1380450-20-3 2,2'-((3-(2-iodoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis((phenylethynyl)benzene) 
• 1380450-21-4 2,2'-((3-(2-iodoethoxy)-1,2-phenylene)bis(ethyne-2,1-diyl))bis(((4-methoxyphenyl)ethynyl)benzene) 
• 1380449-99-9 1-(2-bromoethoxy)-2,3-diiodobenzene 
• 1245635-35-1 2-iodo-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl trifluoromethanesulfonate 

Relevant academic research and scientific papers

Modular Synthesis of Graphene Nanoribbons And Graphene Substructures From Oligo-Alkynes

A method for the synthesis of carbon-based structures, particularly graphene substructures and ribbons, from oligo- and poly-alkyne starting materials.

Polyaromatic ribbons from oligo-alkynes via selective radical cascade: Stitching aromatic rings with polyacetylene bridges

Selective radical generation in conjugated oligomeric o-aryleneethynylenes initiates an intramolecular cascade which involves five fast radical cyclizations followed by aromatization via a 1,5-H shift with a >93% yield per step. This radical cascade trans

Approaches to the synthesis of 2,3-dihaloanilines. Useful precursors of 4-functionalized-1 H-indoles

2,3-Dihaloanilines have been proved as useful starting materials for synthesizing 4-halo-1H-indoles. Subsequent or in situ functionalization of the prepared haloindoles allows the access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles in good overall yields. As no efficient synthetic routes to 2,3-dihaloanilines have been described in the literature, different approaches to the preparation of these 1,2,3-functionalized aromatic precursors are now presented. The most general one involves a Smiles rearrangement from the corresponding 2,3-dihalophenols and allows the preparation of 2,3-dihaloanilides in a straightforward and synthetically useful manner.

Synthesis of 4-functionalized-1H-indoles from 2,3-dihalophenols

A new synthesis of 4-halo-1H-indoles has been developed from easily available 2,3-dihalophenol derivatives. The key steps are Smiles rearrangement and a one-pot or stepwise Sonogashira coupling/NaOH-mediated cyclization. Subsequent functionalization allows access to a wide variety of 2,4- or 2,3,4-regioselectively functionalized indoles.

A new and efficient synthesis of 4-functionalized benzo[6]furans from 2,3-dihalophenols

Tandem Sonogashira coupling/5-endo-dig cyclization reactions on 2,3-dihalophenols suppose a straightforward entry to 4-halobenzo[b]furans, which can be easily transformed into 4-functionalized benzo[b]furans, that are difficult to synthesize by other proc