408349-69-9

Upstream product

• 408349-57-5 N-((S)-1-{(S)-1-[(S)-1-(2,3-Dimethoxy-benzylcarbamoyl)-2-methyl-propylcarbamoyl]-2-methyl-propylcarbamoyl}-2-methyl-propyl)-2,3-dimethoxy-benzamide 
• 28130-13-4 L-valinyl-L-valinyl-L-valine 
• 1521-38-6 2,3-dimethoxybenzoic acid 
• 408349-34-8 (S)-2-{(S)-2-[(S)-2-(2,3-Dimethoxy-benzoylamino)-3-methyl-butyrylamino]-3-methyl-butyrylamino}-3-methyl-butyric acid 

Relevant academic research and scientific papers

Di-, tri- and tetrapeptide-linked dicatechol derivatives

Di-, tri- and tetrapeptide linked dicatechol derivatives are prepared by subsequent coupling of 2,3-dimethoxybenzoic acid (2), peptides 3 and 2,3-dimethoxybenzylamine (5) using classical activating conditions (EDC/HOBt or DDC/HOSu). In the final step the methyl ethers at the veratrol units are cleaved to afford the free catechol derivatives 7, which are potential ligands for metal complexes with well defined fixed conformations at the peptide spacers.