40847-09-4

Basic information

• Product Name: N-(phenylalanyl)-N,N-diethylamine
• Synonyms: N-(phenylalanyl)-N,N-diethylamine
• CAS NO: 40847-09-4
• Molecular Weight: 220.315
• Mol File: 40847-09-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-(phenylalanyl)-N,N-diethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(phenylalanyl)-N,N-diethylamine(40847-09-4)
• EPA Substance Registry System: N-(phenylalanyl)-N,N-diethylamine(40847-09-4)

Safety Data

• Hazardous Substances Data: 40847-09-4(Hazardous Substances Data)

Upstream product

• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 3674-06-4 Boc-Phe-ONSu 
• 120125-43-1 (S)-tert-butyl (1-oxo-3-phenyl-1-(piperidin-1-yl)propan-2-yl)carbamate 
• 102292-89-7 (2S)-2-amino-3-phenyl-1-(piperidin-1-yl)propan-1-one 
• 934548-17-1 (S)-N-[2(chloromethyloxycarbonylamino)-3-phenylpropanoyl]piperidine 
• 934548-18-2 (S)-N-[2-(chloromethyloxycarbonylamino)-3-phenylpropanoyl]-N,N-diethylamine 
• 120125-19-1 N,N-diethyl-(S)-2-(tert-butoxycarbonyl)amino-3-phenylpropanamide 
• 934548-16-0 [2-(2,6-dichloro-phenylamino)-phenyl]-acetic acid 1-diethylcarbamoyl-2-phenyl-ethylcarbamoyloxymethyl ester 

Downstream Products

• 1114542-00-5 (S)-N¹,N¹-diethyl-3-phenylpropane-1,2-diamine 
• 934548-18-2 (S)-N-[2-(chloromethyloxycarbonylamino)-3-phenylpropanoyl]-N,N-diethylamine 

Relevant articles and documents

Novel poly(2-oxazoline)s with pendant l-prolinamide moieties as efficient organocatalysts for direct asymmetric aldol reaction

Poly(2-oxazoline)-supported bifunctional organocatalysts have been prepared through a bottom-up protocol, which involves synthesis of well-defined poly(2-oxazoline) precursors bearing amino groups in the side-chains followed by amide coupling with N-Boc-l-proline then deprotection. The resultant l-prolinamido-functionalized polymers have proven to be significantly more active than their monomeric counterparts for the aldolisation of cyclic ketones with several substituted benzaldehydes under neat conditions. By using 15 mol% of the polymer as a catalyst, the direct aldol reaction products were isolated in high yields and with good diastereo- and enantioselectivity. Based on circular dichroism spectrum analysis, the enhancement in catalytic activity is probably related to the conformational changes of the pseudo-peptide scaffold of poly(2-oxazoline)s. In addition, these soluble polymeric catalysts can be recovered and reused by precipitation in ether for five catalytic cycles without significantly diminishing their efficiency.

Chiral primary-tertiary diamine catalysts derived from natural amino acids for syn-aldol reactions of hydroxy ketones

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