40852-52-6Relevant academic research and scientific papers
Process for preparing 2(1H)-quinazolinone derivatives
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, (2008/06/13)
2(1H)-Quinazolinone and quinazolinethione derivatives having excellent pharmacological activities are produced in high yield with high purity by heating the corresponding 3,4-dihydro-2(1H)-quinazolinone or quinazolinethione derivatives together with sulfur in an inert solvent.
1-Polyhaloalkyl-2(1H)-quinazolinone derivatives
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, (2008/06/13)
1-Polyhaloalkyl-2(1H)-quinazoline derivatives of the formula, STR1 wherein R is polyhaloalkyl having C2 -C4 alkyl; and R1, R2 and R3 are individually hydrogen, C1 -C4 alkyl, C1 -C4 alkoxy, nitro, trifluoromethyl or halogen, have excellent anti-inflammatory and analgesic activities with very low toxicity. These quinazolinone derivatives can be prepared, for example, by reacting a trihalogenoacetamidobenzophenone derivative with ammonia.
