40852-77-5Relevant academic research and scientific papers
Metal-free sulfonylation of quinones with sulfonyl hydrazides in water: Facile access to mono-sulfonylated hydroquinones
Li, Bin,Li, Yaqin,Yu, Linqian,Wu, Xiaoyu,Wei, Wanguo
, p. 2760 - 2765 (2017/04/14)
This paper describes a simple and practical protocol for the direct synthesis of monosulfonylated hydroquinones through a transition-metal-free cross-coupling between quinones and sulfonyl hydrazides in water. The procedure tolerates a variety of quinones
Ir-catalyzed C–S coupling of quinones with sulfonyl chloride
Wang, Long,Xie, Yi-Bi,Yang, Quan-Li,Liu, Ming-Guo,Zheng, Kai-Bo,Hu, Yu-lin,Huang, Nian-Yu
, p. 1797 - 1803 (2016/08/25)
Abstract: A concise, efficient method to sulfonyl quinones and sulfonyl-1,4-diols through Ir-catalyzed C–S coupling of quinones with sulfonyl chloride has been developed. Thus, this methodology proves its value as a versatile synthetic tool for a broad ra
Synthesis of arylsulfonyl-quinones and arylsulfonyl-1,4-diols as FabH inhibitors: Pd-catalyzed direct C-sulfone formation by CS coupling of quinones with arylsulfonyl chloride
Ge, Bingyang,Wang, Dawei,Dong, Weifu,Ma, Piming,Li, Yongliang,Ding, Yuqiang
supporting information, p. 5443 - 5446 (2014/12/11)
The Pd-catalyzed direct C-sulfone formation by C-S coupling of quinones with arylsulfonyl chloride has been developed. This methodology provides an effective, convenient method for the synthesis of arylsulfonyl-quinones and arylsulfonyl-1,4-diols, which a
Synthesis and biological evaluation of novel sulfonyl-naphthalene-1,4-diols as FabH inhibitors
Alhamadsheh, Mamoun M.,Waters, Norman C.,Sachdeva, Sarbjot,Lee, Patricia,Reynolds, Kevin A.
supporting information; experimental part, p. 6402 - 6405 (2009/09/30)
A series of analogs of 2-tosylnaphthalene-1,4-diol were prepared and were found to be potent 10-20 nM reversible inhibitors of the Escherichia coli FabH enzyme. The inhibitors were also effective but to a lesser degree (30 nM-5 μM), against the Mycobacter
