40865-50-7 Usage
Uses
Used in Pharmaceutical Industry:
2,7-Diazaspiro[4.5]decane is used as a key intermediate in the synthesis of medicinal compounds for its potential therapeutic properties. It serves as the basis for the creation of various drugs, including atropine and cocaine, which have significant applications in medicine.
Used in Neurological Disorder Treatments:
In the field of neurology, 2,7-Diazaspiro[4.5]decane is used as a starting material for the development of potential treatments for neurological disorders. Its derivatives are studied for their capacity to modulate neurotransmission and potentially alleviate symptoms associated with such conditions.
Used in Anticholinergic Agent Development:
2,7-Diazaspiro[4.5]decane is utilized in the development of anticholinergic agents, which are important in the management of various conditions by blocking the action of acetylcholine, a neurotransmitter.
Used in Synthetic Organic Chemistry:
In the realm of synthetic organic chemistry, 2,7-Diazaspiro[4.5]decane is used as a structural framework for the exploration of novel chemical reactions and synthetic methodologies. Its complex structure presents challenges and opportunities for the advancement of chemical synthesis techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 40865-50-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,8,6 and 5 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 40865-50:
(7*4)+(6*0)+(5*8)+(4*6)+(3*5)+(2*5)+(1*0)=117
117 % 10 = 7
So 40865-50-7 is a valid CAS Registry Number.
InChI:InChI=1/C8H16N2/c1-2-8(6-9-4-1)3-5-10-7-8/h9-10H,1-7H2
40865-50-7Relevant academic research and scientific papers
Synthesis and differential functionalisation of pyrrolidine and piperidine based spirodiamine scaffolds
Weinberg, Kamil,Stoit, Axel,Kruse, Chris G.,Haddow, Mairi F.,Gallagher, Timothy
, p. 4694 - 4707 (2013/07/04)
The synthesis and differential substitution/protection of a series of spirodiamine scaffolds are described. Methods for selective access to the two mono-N-methyl isomers based on 2,7-diazaspiro[4.5]decane are also described. Key precursors associated with this chemistry are prone to rearrangement and methods for circumventing this issue are reported. While direct mono-carbamoylation (Boc) was not efficient, selective deprotection of doubly Boc-protected derivatives derived from symmetrical diamines provided mono-Boc variants. N-Arylation, exemplified by a series of monosubstituted spirodiamines incorporating the 2-chloro-5-pyridyl moiety, which is a privileged nicotinic agonist substructure, has also been carried out to provide monoarylated secondary and tertiary spirodiamines variants.
