40872-10-4Relevant articles and documents
Asymmetric synthesis of (2R,5R)-2,5-diaminohexan-1,6-dioic acid
Bull, Steven D.,Chernega, Alexander N.,Davies, Stephen G.,Moss, William O.,Parkin, Richard M.
, p. 10379 - 10388 (2007/10/03)
Schollkopf's auxiliary 16 was added to bis-lactim iodide 21 to give 1,2- bis[(3S,6R)-3,6-dihydro-2,5-dimethoxy-3-isopropylpyrazin-6-yl]ethane 22 in 50% d.e. Dimer 22 was separated from its diastereoisomer 23 and deprotected using 6M HCl to afford homochiral (2R,5R)-2,5-diaminohexan-1,6-dioic acid 24.