40876-94-6Relevant articles and documents
Visible-light-induced transition metal and photosensitizer free decarbonylative addition of amino-arylaldehydes to ketones
Lang, Yatao,Li, Chao-Jun,Wang, Yi,Zeng, Huiying
, p. 698 - 703 (2022/02/01)
The decarbonylative-coupling reaction is generally promoted by transition metals (via organometallic complexes) or peroxides (via radical intermediates), often at high temperatures to facilitate the CO release. Herein, a visible-light-induced, transition metal and external photosensitizer free decarbonylative addition of benzaldehydes to ketones/aldehydes at room temperature is reported. Tertiary/secondary alcohols were obtained in moderate to excellent yields promoted by using CsF under mild conditions. The detailed mechanistic investigation showed that the reaction proceeded through photoexcitation–decarbonylation of the aldehyde to generate an aromatic anion, followed by its addition to ketones/aldehydes. The reaction mechanism was verified by the density functional theory (DFT) calculations.
Exploration and Development of a C-H-Activated Route to Access the [1,2]Dithiolo[4,3- b ]indole-3(4 H)-thione Core and Related Derivatives
Asquith, Christopher R. M.,Konstantinova, Lidia S.,Tizzard, Graham J.,Laitinen, Tuomo,Coles, Simon J.,Rakitin, Oleg A.,Hilton, Stephen T.
, p. 156 - 160 (2019/01/14)
A robust procedure for the production of [1,2]dithiolo[4,3- b ]indole-3(4 H)-thione analogues using a DABCO/S 2 Cl 2 complex as a sulfur source via a C-H activated approach.
3-Acylindoles Synthesis: Ruthenium-Catalyzed Carbonylative Coupling of Indoles and Aryl Iodides
Wang, Zechao,Yin, Zhiping,Wu, Xiao-Feng
supporting information, p. 4680 - 4683 (2017/09/12)
A novel and convenient procedure for the synthesis of 3-acylindoles from simple indoles and aryl iodides has been established. Through ruthenium-catalyzed carbonylative C-H functionalization of indoles, with Mo(CO)6 as the solid CO source, the desired indol-3-yl aryl ketones were isolated in moderate to good yields. Not only N-alkylindoles but also N-H indoles can be applied here.
