409061-22-9

Usage

Also known as

2-Ethyl-1-piperidinecarboxylic acid 1,1-dimethylethyl ester

Physical state

Colorless to pale yellow liquid

Odor

Faint

Primary use

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Additional applications

Research and development as an organic building block

Safety precautions

May be harmful if inhaled, ingested, or comes into contact with the skin

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 1484-80-6 2-ethylpiperidine 
• 132910-76-0 rac-2-vinylpiperidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 409061-23-0 N-Boc-2-ethyl-6-methylpiperidine 

Relevant academic research and scientific papers

Guanidine hydrochloride as an organocatalyst for N-Boc protection of amino groups

A simple and efficient method for the chemoselective N-Boc protection of the amine moiety in a variety of compounds is described using di-tert-butyl dicarbonate and guanidine hydrochloride as an organocatalyst in ethanol at 35-40°C. Selective mono-N-Boc protection of diamines and chemoselective protection of hydroxylamines without formation of any side products is achieved. Amino acids and peptides are N-Boc protected efficiently in excellent yields under convenient reaction conditions.

Solenopsin derivatives and analogues as fire ant suppressants

The present invention relates to solenopsin alkaloid derivatives which are trans-2,6-disubstituted piperidines according to the structure: wherein R1and R2are selected from a C1to C20saturated or unsaturated linear, cyclic or branch-chained substituted or unsubstituted hydrocarbon group or a substituted or unsubstituted aromatic group, or an ester group. In certain preferred embodiments, where R1or R2contains an unsaturated group, such as an alkenyl group, the double bond in the alkenyl group preferably is found in the hydrocarbon chain between the carbon atom bonded to the piperidine ring and the adjacent carbon atom (α and β carbons).