409097-50-3Relevant articles and documents
Glycine amides as PPARα agonists
Urbahns, Klaus,Woltering, Michael,Nikolic, Susanne,Pernerstorfer, Josef,Bischoff, Hilmar,Dittrich-Wengenroth, Elke,Lustig, Klemens
scheme or table, p. 3376 - 3379 (2010/08/20)
The design, synthesis and pharmacological properties of a novel class of PPARα agonists is described. Compound 2 is a novel, potent and specific glycine amide with oral bioavailability in rodents. The compound is active in vivo and alters plasma lipids in