409305-50-6Relevant academic research and scientific papers
Dual activation in asymmetric allylsilane addition to chiral N-acylhydrazones: Method development, mechanistic studies, and elaboration of homoallylic amine adducts
Friestad, Gregory K.,Korapala, Chandra Sekhar,Ding, Hui
, p. 281 - 289 (2007/10/03)
Chiral N-acylhydrazones derived from commercially available 4-benzyl-2-oxazolidinone provide a rigid, conformationally restricted template to impart facial selectivity in additions to C=N bonds. In the presence of indium(III) trifluoromethanesulfonate [In
Highly diastereoselective indium-mediated allylation of chiral hydrazones
Cook, Gregory R.,Maity, Bikash C.,Kargbo, Robert
, p. 1741 - 1743 (2007/10/03)
Matrix presented. The indium-mediated allylation of chiral hydrazones was investigated. Essentially complete diastereoselectivity and quantitative yields were obtained for substrates derived from both aromatic and aliphatic aldehydes.
Asymmetric allylsilane additions to enantiopure N-acylhydrazones with dual activation by fluoride and In(OTF)3
Friestad,Ding
, p. 4491 - 4493 (2007/10/03)
A mild, convenient, and stereoselective addition of allylsilanes to enantiopure N-acylhydrazones occurs at room temperature upon complementary activation of both the allylsilane and the hydrazone (see scheme; OTf = trifluoromethanesulfonate). The reaction
