409359-25-7

Basic information

• Product Name: 5-Cyano-2-Methoxybenzenesulfonyl chloride
• Synonyms: 5-Cyano-2-Methoxybenzenesulfonyl chloride
• CAS NO: 409359-25-7
• Molecular Formula: C₈H₆ClNO₃S
• Molecular Weight: 231.65614
• Mol File: 409359-25-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-Cyano-2-Methoxybenzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Cyano-2-Methoxybenzenesulfonyl chloride(409359-25-7)
• EPA Substance Registry System: 5-Cyano-2-Methoxybenzenesulfonyl chloride(409359-25-7)

Safety Data

• Hazardous Substances Data: 409359-25-7(Hazardous Substances Data)

Upstream product

• 3424-93-9 4-methoxyphenylacetamide 
• 7719-09-7 thionyl chloride 
• 81592-99-6 5-carbamoyl-2-methoxybenzenesulfonyl chloride 

Downstream Products

• 524743-27-9 5-cyano-N-[2-(4-dimethylaminophenyl)ethyl]-2-methoxybenzenesulfonamide 
• 500303-74-2 5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide 
• 1067904-10-2 C₂₀H₂₄N₂O₃S 
• 409359-27-9 ethyl [2-[2-(5-cyano-2-methoxybenzenesulfonylamino)-ethyl]-5-isopropylphenoxy]acetate 
• 409359-26-8 5-Cyano-N-[2-(4-hydroxy-2-methoxymethoxyphenyl)ethyl]-2-methoxybenzenesulfonamide 

Relevant articles and documents

Design of Benzoxathiazin-3-one 1,1-Dioxides as a New Class of Irreversible Serine Hydrolase Inhibitors: Discovery of a Uniquely Selective PNPLA4 Inhibitor

The design and examination of 4,1,2-benzoxathiazin-3-one 1,1-dioxides as candidate serine hydrolase inhibitors are disclosed, and represent the synthesis and study of a previously unexplored heterocycle. This new class of activated cyclic carbamates provi

5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF

The present invention relates to a 5-amidino-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is an optionally substituted lower alkyl group, an optionally substituted lower alkoxy group, an optionally substituted lower alkenyl group, a cycloalkyl group or a lower acyl group etc.; Q is a hydrogen atom or an optionally substituted lower alkyl group; and Z is a hydrogen atom or a hydroxy group etc., or a pharmaceutically acceptable salt thereof, which exert a potent and selective activated blood coagulation factor X inhibitory activity and is useful as an agent for the prevention or treatment of a disease occurred associating an activated blood coagulation factor X, a pharmaceutical composition comprising the same and an intermediate thereof. These compounds are useful as preventives or remedies for various diseases such as brain infarction, cerebral thrombosis, cerebral embolism, TIA, cerebral vascular jerk, Alzheimer's diseases, myocardial infarction, heart attack, heart failure, thrombosis, pulmonary infarction and pulmonary embolism.

5-AMIDINO-N-(2-AMINOPHENETHYL)-HYDROXYBENZENESULFONAMIDE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND INTERMEDIATE THEREFOR

The present invention relates to a 5-amidino-N-(2-aminophenethyl)-2-hydroxybenzenesulfonamide derivative represented by the general formula: wherein R1 is a hydrogen atom or a lower alkyl group; R2 represents a hydrogen atom, an opti