40939-65-9Relevant academic research and scientific papers
SUSTAINABLE CHEMICAL PROCESS FOR REDUCTION OF NITRO COMPOUNDS (R-NO2) OR NITROSO COMPOUNDS (R-NO) CONTAINING SULPHONIC OR CARBOXYLIC GROUP INTO CORRESPONDING AMINO COMPOUNDS (R-NH2) WITH INHERENT RECYCLE OF ALL ACIDIC STREAMS GENERATED IN SYNTHESIS
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Page/Page column 51; 53-54, (2011/05/06)
The process of the present invention creates a sustainable and closed water loop allowing inherent recycles of all liquid streams generated in the process. The liquid streams generated during the process of the invention are inherently recycled completely, making the process of the present invention a zero liquid discharge process which is environmentally friendly and sustainable. This invention further relates to a sustainable chemical process of reduction of R- NO2 or R-NO into corresponding R-NH2 that produces environmentally friendly R-NH2 in good yields and selectivity with large of mother liquor recycle. The process has a wide scope in that it can be applied to a number of molecules.
Antiparasitic Agents: Part 5 - Synthesis of 4-(Substituted-aryl)amino-7-chloroquinolines as Potential Antimalarial Agents
Chauhan, P. M. S.,Sharma, Satyavan,Bhakuni, D. S.
, p. 1142 - 1145 (2007/10/02)
A series of 4-(4- and 3-substituted-aryl)amino-7-chloroquinolines (11-15, 17, 18, 28) and substituted diphenyl sulphones (8-10, 19-27) have been synthesized and tested for their antiparasitic activity against Plasmodium berghei in mice, Litomosoides carinii in cotton rats and Hymenolepis nana in mice.Of the compounds tested, 11 shows 100percent activity against P. berghei at a dose of 10 mg/kg x 5 days in mice while 23 is effective in eliminating 100percent of the H. nana worms from mice at a single oral dose of 250 mg/kg.
Anti-allergic oxanilate compounds
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, (2008/06/13)
A method of treating mammals for allergy and anaphylactic reactions of a reagin or non-reagin mediated nature which comprises administering prophylactically to said mammal an anti-allergy or anaphylactic reaction effective amount of a compound of the formula STR1 Novel compounds and compositions are also claimed.
