40953-39-7 Usage
Derivative of imidazole
The compound is based on the imidazole ring structure, which is a common building block in many biologically active compounds.
Contains two nitrile groups
Nitrile groups (C≡N) are highly polar and can form strong hydrogen bonds, making them useful for creating stable compounds with specific properties.
Contains a fluorophenyl group
The presence of a fluorine atom on the phenyl ring can affect the electronic properties of the molecule and can be used to modify its reactivity and solubility.
Used in the synthesis of pharmaceuticals and agrochemicals
The compound can be used as a building block for creating a variety of biologically active compounds, including drugs and pesticides.
Potential applications in medicinal chemistry
The compound's properties and reactivity make it a valuable building block for the development of new drugs and other therapeutic agents.
Used as a reagent in organic synthesis
The compound can be used as a reagent to facilitate chemical reactions and create new compounds.
Diverse potential applications in the fields of pharmaceuticals, agrochemicals, and material science
The compound's unique properties and reactivity make it a valuable building block for a variety of applications, including the development of new materials and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 40953-39-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,9,5 and 3 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 40953-39:
(7*4)+(6*0)+(5*9)+(4*5)+(3*3)+(2*3)+(1*9)=117
117 % 10 = 7
So 40953-39-7 is a valid CAS Registry Number.
40953-39-7Relevant academic research and scientific papers
Discovery of cell-active phenyl-imidazole Pin1 inhibitors by structure-guided fragment evolution
Potter, Andrew,Oldfield, Victoria,Nunns, Claire,Fromont, Christophe,Ray, Stuart,Northfield, Christopher J.,Bryant, Christopher J.,Scrace, Simon F.,Robinson, David,Matossova, Natalia,Baker, Lisa,Dokurno, Pawel,Surgenor, Allan E.,Davis, Ben,Richardson, Christine M.,Murray, James B.,Moore, Jonathan D.
scheme or table, p. 6483 - 6488 (2010/12/18)
Pin1 is an emerging oncology target strongly implicated in Ras and ErbB2-mediated tumourigenesis. Pin1 isomerizes bonds linking phospho-serine/threonine moieties to proline enabling it to play a key role in proline-directed kinase signalling. Here we report a novel series of Pin1 inhibitors based on a phenyl imidazole acid core that contains sub-μM inhibitors. Compounds have been identified that block prostate cancer cell growth under conditions where Pin1 is essential.
Imidazoles and their compositions for plant growth regulation
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, (2008/06/13)
The invention provides a method of regulating the growth of a plant using a compound of the formula: wherein R1 represents alkyl or phenyl optionally substituted by halogen, alkyl, alkoxy, alkylthio, trifluoromethyl, trifluoromethoxy, trifluoromethylthio,
