40995-06-0Relevant academic research and scientific papers
Dinitrofuroxan cycloreversion as a novel general approach for the synthesis of nitroazoles
Fershtat,Khakimov,Makhova
, p. 415 - 422 (2015/10/29)
A novel general approach towards various nitroazoles via tandem process involving dinitrofuroxan cycloreversion followed by [3+2] cycloaddition of generated in situ nitroformonitrile oxide is developed. The reaction is promoted by addition of catalytic am
Ionic liquid-promoted [3+2]-cycloaddition reactions of nitroformonitrile oxide generated by the cycloreversion of dinitrofuroxan
Fershtat, Leonid L.,Ovchinnikov, Igor V.,Makhova, Nina N.
supporting information, p. 2398 - 2400 (2014/05/06)
A new approach to the synthesis of 3-nitroisoxazoles and 3-nitroisoxazolines based on the [3+2]-cycloaddition of nitroformonitrile oxide (NFNO), generated by the cycloreversion of dinitrofuroxan (DNFO), to acetylene and ethylene derivatives, under ionic liquid catalysis is developed. The approach is of a general nature and applicable to cycloaddition reactions with other dipolarophiles.
Unexpected heterocyclization of electrophilic alkenes by tetranitromethane in the presence of triethylamine. Synthesis of 3-nitroisoxazoles
Volkova, Yulia A.,Averina, Elena B.,Grishin, Yuri K.,Bruheim, Per,Kuznetsova, Tamara S.,Zefirov, Nikolai S.
supporting information; experimental part, p. 3047 - 3052 (2010/07/15)
Novel reaction of tetranitromethane (TNM) with electrophilic alkenes in the presence of triethylamine yielding substituted 3-nitroisoxazoles was found and studied. Triethylamine increases the reactivity of TNM toward electrophilic alkenes promoting their heterocyclization, and the reactions proceed in an unusual way. A variety of α,β-unsaturated aldehydes, ketones, esters, amides, phosphonates, and nitro and sulfur compounds was involved in the heterocyclization reaction, and a wide range of functionalized 3-nitroisoxazoles was obtained in good to high yields. The scope and limitations of the reaction and the mechanistic aspects are discussed.
3-NITROISOXAZOLES AND THEIR USE IN THE PROTECTION OF MATERIALS
-
, (2012/09/11)
The 3-nitroisoxazoles of the formula (I) in which R1 and R2 are each as defined in the description, some of which are known, are highly suitable for use as biocides for protecting industrial materials.
SINTESI ED ATTIVITA' ANTIMICROBICA IN VITRO DI DERIVATI 3-NITROISOSSAZOLICI
Duranti, E.,Balsamini, C.,Scheda, P.
, p. 299 - 306 (2007/10/02)
Some azomethine type compounds from 3-nitroisoxazol-5-carboxy-aldehyde were synthesized; among these the most active, oxime (III a), shows bacteriostatic activity in vitro against gram- comparable to that of nitrofurantoin.
