40995-46-8 Usage
Heterocyclic compound
Pyrazole and pyridazine rings
The compound has a pyrazole ring (a five-membered ring with two nitrogen atoms) fused to a pyridazine ring (a six-membered ring with four nitrogen atoms).
Methyl group attachment
Nitrogen atom
A methyl group (a carbon atom bonded to three hydrogen atoms) is attached to one of the nitrogen atoms in the compound.
Pharmaceutical properties
Anti-inflammatory and antibacterial
The compound has been studied for its potential use in treating inflammation and bacterial infections.
Building block for synthesis
Organic compounds
1-Methyl-1H-pyrazolo[4.3-d]pyridazin-4(5H)-one is being investigated as a starting material for the synthesis of other organic compounds.
Unique structure
Potential biological activity
The compound's structure makes it an interesting target for further research and development in medicinal chemistry due to its potential biological activity.
Check Digit Verification of cas no
The CAS Registry Mumber 40995-46-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,9,9 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 40995-46:
(7*4)+(6*0)+(5*9)+(4*9)+(3*5)+(2*4)+(1*6)=138
138 % 10 = 8
So 40995-46-8 is a valid CAS Registry Number.
40995-46-8Relevant academic research and scientific papers
AZOLE-FUSED PYRIDAZIN-3(2H)-ONE DERIVATIVES
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Paragraph 0187; 0188, (2021/04/01)
Disclosed are compounds of Formula (1) and pharmaceutically acceptable salts thereof, wherein α, β, n, R4, R5, R6, R8, R9, R10, R11, X1, X2, X3 and X7 are defined in the specification. This disclosure also relates to materials and methods for preparing compounds of Formula (1), to pharmaceutical compositions comprising them, and to their use for treating diseases, disorders, and conditions associated with GPR139.
Synthesis of Pyrazolopyridazines from 5-(1-Methylhydrazino)-pyridazines by Means of the Vilsmeier-Haack Reaction
Kaji, Kenji,Nagashima, Hiromu,Hirose, Yoshihiko,Oda, Hirohisa
, p. 982 - 988 (2007/10/02)
Reaction of 2-substituted 5-(1-methylhydrazino)-3(2H)-pyridazinones (2a-d) with dimethylformamide-phosphorus oxychloride afforded 5-substituted 1,5-dihydro-1-methyl-4H-pyrazolopyridazin-4-ones (3a-d) in good yields.However, concurrent formation of
