4100-17-8

Basic information

• Product Name: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)
• Synonyms: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI);1,2,3-Thiadiazole-4-carbonyl chloride ,97%
• CAS NO: 4100-17-8
• Molecular Formula: C₃HClN₂OS
• Molecular Weight: 148.573
• Product Categories: ACIDHALIDE
• Mol File: 4100-17-8.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)(4100-17-8)
• EPA Substance Registry System: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)(4100-17-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 4100-17-8(Hazardous Substances Data)

Usage

General Description

1,2,3-Thiadiazole-4-carbonyl chloride is a chemical compound with the molecular formula C2HClN2OS. It is a colorless to light yellow liquid with a pungent odor, and it is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI) is an important building block in the preparation of various heterocyclic compounds and is utilized in the pharmaceutical industry for the synthesis of new drug candidates. Additionally, it is also used in the preparation of compounds with potential pesticidal and herbicidal properties. The compound exhibits reactivity as a versatile acylating agent, and it is typically handled and stored under strict safety measures due to its corrosive nature.

Upstream product

• 4100-13-4 1,2,3-thiadiazole-4-carboxylic acid 

Downstream Products

• 27053-30-1 N-Aethyl-1,2,3-thiadiazol-4-carboxamid 
• 4100-22-5 1,2,3-Thiadiazol-4-carbonsaeure-anilid 
• 4100-37-2 [1,2,3]thiadiazole-4-carboxylic acid N'-benzenesulfonyl-hydrazide 
• 4100-18-9 1,2,3-thiadiazolylcarboxylic acid hydrazide 
• 4100-26-9 [1,2,3]thiadiazole-4-carbonyl azide 
• 4100-20-3 1,2,3-thiadiazole-4-carboxamide 
• 436863-78-4 benzoic acid N'-([1,2,3]thiadiazole-4-carbonyl)-hydrazide 
• 436863-80-8 [1,2,3]thiadiazole-4-carboxylic acid N'-phenyl-N'-([1,2,3]thiadiazole-4-carbonyl)-hydrazide 
• 436863-79-5 C₁₀H₁₀N₄O₃S₂ 

Relevant articles and documents

Synthesis and antifungal activities of alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamates and S-alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamothioates

A series of alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamates and S-alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamothioates with unsubstituted or monobrominated straight chain alkyl groups were synthesized and evaluated as fungistatic agents against Gibberella zeae and Altemaria kikuchiana. These compounds showed variable antifungal activities at concentrations of 5 and 50 μg/mL The results showed that antifungal activities depended on the length of the alkyl chain with the optimal chain length of 6-11 carbons. Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, hexyl ester (4) showed a strong fungistatic activity against A. kikuchiana at both concentrations, with 90.7 and 54% growth inhibition at 50 and 5 μg/mL, respectively. Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, heptyl ester (5); Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, octyl ester (6); and Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, undecyl ester (9) showed strong fungistatic activity against G. zeae at both concentrations. Their growth inhibitions against G. zeae at the concentration of 5 μg/mL were 78, 63, and 59%, respectively.