4100-17-8

Basic information

• Product Name: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)
• Synonyms: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI);1,2,3-Thiadiazole-4-carbonyl chloride ,97%
• CAS NO: 4100-17-8
• Molecular Formula: C₃HClN₂OS
• Molecular Weight: 148.573
• Product Categories: ACIDHALIDE
• Mol File: 4100-17-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)(4100-17-8)
• EPA Substance Registry System: 1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI)(4100-17-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 4100-17-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI) is used as an intermediate for the synthesis of new drug candidates, contributing to the development of innovative pharmaceuticals with potential therapeutic applications.
Used in Agrochemical Industry:
1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI) is used in the preparation of compounds with potential pesticidal and herbicidal properties, aiding in the development of effective solutions for crop protection and pest management.
Used in Organic Synthesis:
1,2,3-Thiadiazole-4-carbonyl chloride (6CI,7CI,8CI,9CI) is used as a versatile acylating agent in the synthesis of various heterocyclic compounds, enabling the creation of a wide range of organic compounds with diverse applications.

Upstream product

• 4100-13-4 1,2,3-thiadiazole-4-carboxylic acid 

Downstream Products

• 27053-30-1 N-Aethyl-1,2,3-thiadiazol-4-carboxamid 
• 4100-22-5 1,2,3-Thiadiazol-4-carbonsaeure-anilid 
• 4100-37-2 [1,2,3]thiadiazole-4-carboxylic acid N'-benzenesulfonyl-hydrazide 
• 4100-18-9 1,2,3-thiadiazolylcarboxylic acid hydrazide 
• 4100-26-9 [1,2,3]thiadiazole-4-carbonyl azide 
• 4100-20-3 1,2,3-thiadiazole-4-carboxamide 
• 436863-79-5 C₁₀H₁₀N₄O₃S₂ 
• 436863-80-8 [1,2,3]thiadiazole-4-carboxylic acid N'-phenyl-N'-([1,2,3]thiadiazole-4-carbonyl)-hydrazide 
• 436863-78-4 benzoic acid N'-([1,2,3]thiadiazole-4-carbonyl)-hydrazide 

Relevant articles and documents

Synthesis and antifungal activities of alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamates and S-alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamothioates

A series of alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamates and S-alkyl N-(1,2,3-thiadiazole-4-carbonyl) carbamothioates with unsubstituted or monobrominated straight chain alkyl groups were synthesized and evaluated as fungistatic agents against Gibberella zeae and Altemaria kikuchiana. These compounds showed variable antifungal activities at concentrations of 5 and 50 μg/mL The results showed that antifungal activities depended on the length of the alkyl chain with the optimal chain length of 6-11 carbons. Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, hexyl ester (4) showed a strong fungistatic activity against A. kikuchiana at both concentrations, with 90.7 and 54% growth inhibition at 50 and 5 μg/mL, respectively. Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, heptyl ester (5); Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, octyl ester (6); and Carbamic acid, (1,2,3-thiadiazole-4-ylcarbonyl)-, undecyl ester (9) showed strong fungistatic activity against G. zeae at both concentrations. Their growth inhibitions against G. zeae at the concentration of 5 μg/mL were 78, 63, and 59%, respectively.

Thiourea inhibitors of herpes viruses. Part 1: Bis-(aryl)thiourea inhibitors of CMV

Bis-(aryl)thioureas were found to be potent and selective inhibitors of cytomegalovirus (CMV) in cultured HFF cells. Of these, the thiazole analogue 38 was investigated as a potential development candidate.