410076-93-6Relevant academic research and scientific papers
Conformationally restricted triplex-forming oligonucleotides (TFOs). Binding properties of α-l-LNA and introduction of the N7-glycosylated LNA-guanosine
Koshkin, Alexei A.
, p. 5962 - 5972 (2007/10/03)
The method for scaled-up production of α-l-LNA phosphoramidite building blocks containing thymine and 5-methylcytosine nucleobases is described. Binding properties of pyrimidine TFOs modified with α-l-LNA are reported. In contrast to LNA TFOs, the fully m
&α-L-ribo-Configured Locked Nucleic Acid (&α-L-LNA): Synthesis and Properties
Soerensen, Mads D.,Kvaernoe, Lisbet,Bryld, Torsten,Hakansson, Anders E.,Verbeure, Birgit,Gaubert, Gilles,Herdewijn, Piet,Wengel, Jesper
, p. 2164 - 2176 (2007/10/03)
The syntheses of monomeric nucleosides and 3'-O-phosphoramidite building blocks en route to α-L-ribo-configured locked nucleic acids (α-L-LNA), composed entirely of α-L-LNA monomers (α-L-ribo configuration) or of a mixture of α-L-LNA and DNA monomers (β-D
