410077-71-3

Upstream product

• 132969-71-2 methyl (2S)-[(4-methoxybenzyl)oxy]-2-methylpropanoate 
• 939-26-4 2-bromomethylnaphthyl bromide 
• 185203-71-8 methyl (S)-N-methyl-N-methoxy-3-(4-methoxybenzyloxy)-2-methylpropanoate 
• 410077-39-3 (S)-1-(tert-Butyl-diphenyl-silanyloxy)-2-methyl-3-(R)-oxiranyl-propan-2-ol 
• 410077-46-2 (2S,5R)-6-(4-Methoxy-benzyloxy)-5-methyl-4-methylene-1-((S)-2-methyl-oxiranyl)-hexan-2-ol 
• 410077-70-2 (2S,4S,7R)-8-(4-Methoxy-benzyloxy)-2,7-dimethyl-6-methylene-octane-1,2,4-triol 
• 410077-35-9 carbonic acid tert-butyl ester 1-(tert-butyl-diphenyl-silanyloxymethyl)-1-methyl-but-3-enyl ester 
• 410077-37-1 (4S,6R)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-6-iodomethyl-4-methyl-[1,3]dioxan-2-one 
• 410077-28-0 Triethyl-[(S)-3-(naphthalen-2-ylmethoxy)-1-(S)-1-oxiranylmethyl-propoxy]-silane 
• 410077-64-4 3-(naphthalen-2-ylmethoxy)-propionaldehyde 
• 410077-45-1 1-(tert-butyl-diphenyl-silanyloxy)-6-[2-(4-methoxy-benzyloxy)-1-methyl-ethyl]-2-methyl-hept-6-ene-2,4-diol 
• 410077-69-9 1-(tert-butyl-diphenyl-silanyloxy)-2-methyl-pent-4-en-2-ol 
• 410077-41-7 (S)-4-(4-Methoxy-benzyloxy)-3-methyl-butan-2-one 
• 56599-24-7 p-methoxybenzyl trichloroacetate 

Downstream Products

• 410077-73-5 Acetic acid (2R,4S,6S,8S,10S)-8-[(R)-4-(4-methoxy-benzyloxy)-3-methyl-2-methylene-butyl]-10-methyl-2-(2-oxo-ethyl)-10-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 410077-53-1 Acetic acid (2S,4S,6R,8S,10S)-2-(2-hydroxy-ethyl)-8-[(R)-4-(4-methoxy-benzyloxy)-3-methyl-2-methylene-butyl]-10-methyl-10-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 410077-74-6 {(2R,4S,6S,8S,10S)-4-Acetoxy-8-[(R)-4-(4-methoxy-benzyloxy)-3-methyl-2-methylene-butyl]-10-methyl-10-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-2-yl}-acetic acid 
• 410077-55-3 C₄₃H₇₄O₉Si₂ 
• 410077-81-5 C₆₅H₁₁₂O₁₅Si₃ 
• 410077-72-4 Acetic acid (2S,4S,6R,8S,10S)-8-[(R)-4-(4-methoxy-benzyloxy)-3-methyl-2-methylene-butyl]-10-methyl-2-[2-(naphthalen-2-ylmethoxy)-ethyl]-10-triethylsilanyloxy-1,7-dioxa-spiro[5.5]undec-4-yl ester 

Relevant academic research and scientific papers

Spongistatin synthetic studies. An efficient, second-generation construction of an advanced ABCD intermediate

(formula presented) A short, efficient, and stereocontrolled synthesis of (-)-4, an advanced ABCD subunit of the spongistatins, has been achieved. Central to the synthetic strategy is the multicomponent linchpin union of silyl dithianes with epoxides to access both the AB and CD fragments. Fragment coupling was then achieved via an efficient stereoselective aldol reaction. The linear sequence required 22 steps and proceeded in 4.0% overall yield.