410079-22-0Relevant academic research and scientific papers
Prodrug of an ice inhibitor
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Page/Page column 16, (2016/11/24)
This invention describes an ICE inhibitor prodrug (I) having good bioavailability. Compound I is useful for treating IL-1 mediated diseases such as rheumatoid arthritis, inflammatory bowel disease, Crohn's disease, ulcerative colitis, inflammatory periton
C-terminal modified oxamyl dipeptides as inhibitors of the ICE-ced-3 family of cysteine proteases
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, (2008/06/13)
This invention is directed to novel oxamyl dipeptide ICE/ced-3 family inhibitor compounds. The invention is also directed to pharmaceutical compositions containing these compounds, as well as to the use of such compositions in the treatment of patients su
