41018-19-3

Basic information

• Product Name: Phosphoramidic dichloride, [[(2,4-dimethylphenyl)amino]carbonyl]-
• CAS NO: 41018-19-3
• Molecular Formula: C9H11Cl2N2O2P
• Molecular Weight: 281.078
• Mol File: 41018-19-3.mol

Chemical Properties

• CAS DataBase Reference: Phosphoramidic dichloride, [[(2,4-dimethylphenyl)amino]carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoramidic dichloride, [[(2,4-dimethylphenyl)amino]carbonyl]-(41018-19-3)
• EPA Substance Registry System: Phosphoramidic dichloride, [[(2,4-dimethylphenyl)amino]carbonyl]-(41018-19-3)

Safety Data

• Hazardous Substances Data: 41018-19-3(Hazardous Substances Data)

Upstream product

• 870-30-4 isocyanatophosphonic dichloride 
• 95-68-1 2,4-Xylidine 

Relevant articles and documents

Synthesis and antimicrobial activity of N-(substituted)-N'-(2,3-dihydro-2-oxido-5-benzoyl-1H-1,3,2-benzodiazaphosphol-2-yl) ureas.

N-(substituted)-N'-(2,3-dihydro-5-benzoyl-2-oxido-1H-1,3,2-benzodiazaphosphol-2-yl) ureas were synthesized by reacting 3,4-diaminobenzophenone (4) with different chlorides of carbamidophosphoric acids (3) in the presence of triethylamine at 40-45 degrees C. Their 1H-, 13C- and 31P-NMR spectral data are discussed. The title compounds were screened for antifungal and antibacterial activity against the fungi Aspergillus niger and Fusarium solani and bacteria Escherichia coli and Staphylococcus aureus. These compounds showed higher antibacterial activity when compared with antifungal activity.

Synthesis and antimicrobial activity of 1-[(substituted carbamoyl)amino]-1H,3H-1λ5-[1,3,2]oxazaphospholo[3,4-a] benzimidazol-1-ones

1-[(Substituted carbamoyl)amino]-1H,3H-1λ5-[1,3,2]oxazaphospholo[3, 4-a]benzimidazol-1-ones were synthesized by reacting benzimidazole 2-methanol (4) with different chlorides of carbamidophosphoric acids (3) in the presence of triethylamine at 40-45°C. Th

Synthesis and antimicrobial activity of some new N-(substituted phenyl)-N′-[2,3-dihydro-2-oxido-3-(4′-fluorophenyl)-1H-(1,3,2) benzoxazaphosphorin 2-yl]ureas

(Chemical Equation Presented) Substituted benzoxazaphosphorin 2-yl ureas were synthesized by reacting 2-(4-fluoro-phenylamino)-methylphenol (4) with different carbamidophosphoric acid dichlorides (3) in the presence of triethylamine in dry toluene at 45-50°C and characterized by spectral data. These compounds were found to possess good antimicrobial activity.

Synthesis of N-(Substituted)-N′-[5,5′-bis(bromomethyl)-2-oxido- 1,3,2-dioxaphosphorinane-2yl] ureas

Synthesis of N-(Substituted)-N′-[5,5′bis(bromomethyl)-2-oxido- 1,3,2-dioxaphosphorinane-2yl] ureas has been accomplished by condensation of equimolar quantities of chlorides of various carbamidophosphoric acids 3 with 2,2′-bis(bromomethyl)l,3-propanediol

Synthesis and antimicrobial activity of N-(substituted)-N′-[1,2,4, 8,10,11-hexachloro-6-oxido-12H-dibenzo(d,g)(1,3,2)-dioxaphosphocin-6-yl]ureas

Substituted dibenzo dioxaphosphocin-6-yl ureas were synthesized by reacting hexachlorophene (4) with different carbamidophosphoric acid dichlorides (3) in the presence of triethylamine in dry toluene at 45-50 °C. Their IR, 1H, 13C and 31P NMR spectral data is discussed. These compounds were found to possess good antimicrobial activity.

Synthesis of N-(substituted aryl/cyclohexyl)-N′-[5-bromo-5-nitro-2-oxido-1,3, 2-dioxaphosphorinane-2-yl]ureas

N-(Substituted aryl/cyclohexyl)-N′-[5-bromo-5-nitro-2-oxido-1,3, 2-dioxaphosphorinane-2-yl]ureas RR′P(O)NHC(O)NHR" (5) were synthesized by the reactions of 2-bromo-2-nitro-1,3-propanediol (4) with chlorides of aryl/cyclohexyl carbamidophosphoric acids (3) in the presence of triethylamine at room temperature. Their ir, 1H, 13C and 31P nmr spectral data are discussed.

Synthesis and antimicrobial activity of N-substituted N′-[6-methyl-2-oxido-1,3,2-dioxaphosphinino(5,4-b)pyride-2-yl]ureas

N-Substituted N′-[6-methyl-2-oxido-1,3,2-dioxaphosphinino(5,4,-b)pyridine-2-yl]ureas have been accomplished by condensation of equimolar quantities of chlorides of various carbamidophosphoric acids (3) with 3-hydroxyl-6-methyl-2-pyridinemethanol (lutidine diol) (4) in the presence of triethylamine in dry toluene-tetrahydrofuran (1:1) mixture at 45-50°C. Their structures were established by elemental analyses, IR, 1H NMR, 13C NMR, and 31P NMR spectral data. Their antifungal and antibacterial activity is also evaluated. Most of these compounds exhibited moderate antimicrobial activity in the assays.

Synthesis and antimicrobial activity of N-(substitutedphenyl)-N'-[1,2,3,4-tetrahydro-2-oxido- 1,3,2-benzodiazaphosphorine-2-y1] ureas

N-(Substitutedphenyl)-N′-[1,2,3,4-tetrahydro-2-oxido- 1,3,2-benzodiazaphosphorine-2-y1] ureas 5 which are substituted ureas of the type RR′P(O)NHC(O)NR″R? have been synthesized from reactions of 2-aminobenzylamine 2 with chlorides of arylcarbamidophosphor