410527-84-3Relevant academic research and scientific papers
PRO_SELECT: Combining structure-based drug design and array-based chemistry for rapid lead discovery. 2. The development of a series of highly potent and selective factor Xa inhibitors
Liebeschuetz, John W.,Jones, Stuart D.,Morgan, Phillip J.,Murray, Chris W.,Rimmer, Andrew D.,Roscoe, Jonathan M.E.,Waszkowycz, Bohdan,Welsh, Pauline M.,Wylie, William A.,Young, Stephen C.,Martin, Harry,Mahler, Jacqui,Brady, Leo,Wilkinson, Kay
, p. 1221 - 1232 (2007/10/03)
In silico screening of combinatorial libraries prior to synthesis promises to be a valuable aid to lead discovery. PRO_SELECT, a tool for the virtual screening of libraries for fit to a protein active site, has been used to find novel leads against the se
