410545-63-0Relevant academic research and scientific papers
A potent and orally active HIV-1 integrase inhibitor
Egbertson, Melissa S.,Moritz, H. Marie,Melamed, Jeffrey Y.,Han, Wei,Perlow, Debra S.,Kuo, Michelle S.,Embrey, Mark,Vacca, Joseph P.,Zrada, Matthew M.,Cortes, Amanda R.,Wallace, Audrey,Leonard, Yvonne,Hazuda, Daria J.,Miller, Michael D.,Felock, Peter J.,Stillmock, Kara A.,Witmer, Marc V.,Schleif, William,Gabryelski, Lori J.,Moyer, Gregory,Ellis, Joan D.,Jin, Lixia,Xu, Wei,Braun, Matthew P.,Kassahun, Kellem,Tsou, Nancy N.,Young, Steven D.
, p. 1392 - 1398 (2007)
A 1,6-naphthyridine inhibitor of HIV-1 integrase has been discovered with excellent inhibitory activity in cells, good pharmacokinetics, and an excellent ability to inhibit virus with mutant enzyme.
