4106-24-5 Usage
Heterocyclic organic compound
The compound contains a benzene ring fused to a seven-membered ring, which includes carbon and nitrogen atoms, making it a heterocyclic compound.
Benzene ring
A six-membered ring structure with alternating single and double bonds, which is a common structural motif in organic chemistry.
Seven-membered ring
The compound has a seven-membered ring composed of four carbon atoms and three nitrogen atoms, which is relatively rare in organic compounds.
Fused ring system
The benzene ring is fused to the seven-membered ring, creating a complex structure with multiple rings.
Indazole derivative
1-PHENYL-1,3,4,5-TETRAHYDRO-BENZO[CD]INDAZOLE is derived from indazole, a bicyclic compound consisting of a benzene ring fused to a five-membered nitrogen-containing ring.
Potential applications in medicinal chemistry
This chemical may have biological activities that could be of interest for pharmaceutical research and development, making it a potential candidate for drug discovery and design.
Biological activities
The compound may exhibit various biological activities, which could be useful for treating diseases or understanding cellular processes. Further research is needed to determine the specific activities and potential applications of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 4106-24-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,0 and 6 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 4106-24:
(6*4)+(5*1)+(4*0)+(3*6)+(2*2)+(1*4)=55
55 % 10 = 5
So 4106-24-5 is a valid CAS Registry Number.
InChI:InChI=1/C16H14N2/c1-2-8-13(9-3-1)18-15-11-5-7-12-6-4-10-14(17-18)16(12)15/h1-3,5,7-9,11H,4,6,10H2
4106-24-5Relevant articles and documents
Synthesis of 1-aryl-1H-indazoles via palladium-catalyzed intramolecular amination of aryl halides
Lebedev, Artyom Y.,Khartulyari, Anton S.,Voskoboynikov, Alexander Z.
, p. 596 - 602 (2007/10/03)
(Chemical Equation Presented) Palladium-catalyzed cyclization of arylhydrazones of 2-bromoaldehydes and 2-bromoacetophenones to give 1-aryl-1H-indazoles has been studied in detail. The cyclization of arylhydrazone of 2-bromobenzaldehydes can be performed with good to high yields using Pd(dba)2 and chelating phosphines, of which the most effective are rac-BINAP, DPEphos, and dppf, in the presence of Cs2CO3 or K3PO4 as a base. Electron-rich, bulky ligands commonly employed for intermolecular amination such as PtBu3 and o-PhC6H4PtBu2 were shown to be ineffective for cyclization and to lead instead to extensive oligomerization and tarring. The method developed is applicable for preparation of a wide scope of indazoles bearing electron-donating or electron-withdrawing substituents, among them, unprotected carboxyl, as well as various indazole heteroanalogues. The cyclization of arylhydrazones of less reactive halides such as 2-chlorobenzaldehyde, as well as 2-bromoacetophenone and bromotetralone, has been achieved. The purity of the starting hydrazone has been shown to be a critical parameter, as various impurities inhibit the cyclization.
