41063-36-9Relevant academic research and scientific papers
Regioselective ring-opening of epoxides with amines using Zn(ClO4)2-Al2O3 as a heterogeneous and recyclable catalyst
Maheswara, Muchchintala,Rao, Kummari Subba Venkata Krishna,Do, Jung Yun
, p. 1795 - 1800 (2008/09/18)
A simple and efficient method has been developed for the synthesis of β-amino alcohols by regioselective ring-opening of epoxides with amines in the presence of zinc perchlorate-neutral alumina as a heterogeneous recyclable catalyst at room temperature in high yields.
Scandium triflate as an efficient and useful catalyst for the synthesis of β-amino alcohols by regioselective ring opening of epoxides with amines under solvent-free conditions
Placzek, Andrew T.,Donelson, James L.,Trivedi, Rushi,Gibbs, Richard A.,De, Surya K.
, p. 9029 - 9034 (2007/10/03)
A simple and efficient method has been developed for the synthesis of β-amino alcohols by ring opening of epoxides in the presence of a catalytic amount of Sc(OTf)3 at room temperature under solvent-free conditions. The reaction works well with both aromatic and aliphatic amines. High regio-, and diastereoselectivity can be considered as a noteworthy advantage of this method.
