4107-64-6

Basic information

• Product Name: pyrene-1-carbonitrile
• Synonyms: 1-Cyanopyrene; 1-pyrenecarbonitrile; PYRENECARBONITRILE
• CAS NO: 4107-64-6
• Molecular Formula: C₁₇H₉N
• Molecular Weight: 227.2601
• Mol File: 4107-64-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 446°C at 760 mmHg
• Flash Point: 225.2°C
• Density: 1.29g/cm³
• Vapor Pressure: 3.76E-08mmHg at 25°C
• Refractive Index: 1.817
• CAS DataBase Reference: pyrene-1-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: pyrene-1-carbonitrile(4107-64-6)
• EPA Substance Registry System: pyrene-1-carbonitrile(4107-64-6)

Safety Data

• Hazardous Substances Data: 4107-64-6(Hazardous Substances Data)

Upstream product

• 129-00-0 pyrene 
• 143-33-9 sodium cyanide 
• 1369323-66-9 2'-O-(pyren-1-ylmethanimine-N-oxymethyl)guanosine 
• 1369323-61-4 2'-O-(pyren-1-ylmethanimine-N-oxymethyl)adenosine 
• 1369323-53-4 2'-O-(pyren-1-ylmethanimine-N-oxymethyl)cytidine 
• 1369323-43-2 2'-O-(pyren-1-ylmethanimine-N-oxymethyl)uridine 
• 3029-19-4 pyrene-1-aldehyde 
• 1369323-51-2 2'-O-(aminooxymethyl)cytidine 
• 1369323-42-1 2'-O-(aminooxymethyl)uridine 

Relevant articles and documents

2'-O-AMINOOXYMETHYL NUCLEOSIDE DERIVATIVES FOR USE IN THE SYNTHESIS AND MODIFICATION OF NUCLEOSIDES, NUCLEOTIDES AND OLIGONUCLEOTIDES

Disclosed are O-protected compounds of the formula (I):wherein B is an optionally protected nucleobase, and R1-R3 are as described herein, a method of preparing such compounds, and a method of preparing oligonucleotides such as RNA starting from such compounds. The O-protected compounds have one or more advantages, for example, the 2'-O-protected compound is stable during the various reaction steps involved in oligonucleotide synthesis; the protecting group can be easily removed after the synthesis of the oligonucleotide, for example, by reaction with tetrabutylammonium fluoride; and/or the O-protected groups do not generate DNA/RNA alkylating side products, which have been reported during removal of 2'-O-(2-cyanoethyl)oxymethyl or 2'-O-[2-(4-tolylsulfonyl)ethoxymethyl groups under similar conditions.