41106-03-0

Upstream product

• 487-68-3 mesytaldehyde 
• 4229-44-1 N-methylhydroxyamine hydrochloride 

Downstream Products

• 1393602-66-8 5-(2,4,6-trimethylbenzylidene)pyrimidine-2,4,6(1H,3H,5H)-trione 
• 54689-97-3 2-(2,4,6-trimethylbenzylidene)-2H-indene-1,3-dione 
• 683213-98-1 2-(2,4,6-trimethylbenzylidene)malonic acid 
• 139484-16-5 5,5-dimethyl-2-(2,4,6-trimethylbenzylidene)cyclohexane-1,3-dione 
• 53389-56-3 (E)-4-mesityl-3-buten-2-one 
• 1440425-52-4 C₃₆H₄₀Cl₂N₄O₂Pd 
• 72261-78-0 N-methyl trimethyl-2,4,6,benzamide 
• 1401089-58-4 trans-[PtCl₂{N=C(Ph)ON(Me)C(H)(C₆H₂Me₃-2,4,6)}(benzonitrile)] 
• 100367-27-9 2,6-dimethyl-3,7-bis(2,4,6-trimethylphenyl)-2,3,6,7-tetrahydrobenzo<1,2-d:4,5-d'>diisoxazole 

Relevant academic research and scientific papers

Synthesis, molecular structure, spectroscopic properties and stability of (Z)-N-methyl-C-2,4,6-trimethylphenylnitrone This paper is dedicated to our wonderful friend Dr. Samir Senior from Alexandria University (Egypt) who recently passed away.

New N-methyl-C-2,4,6-trimethylphenylnitrone 1 has been synthesized starting from N-methylhydroxylamine and mesitaldehyde. The product was fully characterized using different spectroscopic techniques; FTIR, NMR, UV-Vis, high resolution mass spectrometry an

The effects of lewis acid on the 1,3-dipolar cycloaddition reaction of C-arylaldonitrones with alkenes

The regio- and stereoselectivity of the 1,3-dipolar cycloaddition reactions of C-aryl-N-alkylaldonitrones (1a-e) with some alkenes were found to be affected significantly by the addition of Lewis acid. The rate of the reaction was also affected by adding the Lewis acid. In the reactions using allyl alcohol as a dipolarophile an addition of Lewis acid caused a remarkable acceleration of the reaction and a great change in the stereoselectivity. In the reactions using ethyl acrylate as a dipolarophile the regioselectivity was reversed whether the reaction was performed in the presence or the absence of Lewis acid; i.e. isoxazolidine-5-carboxylates were obtained mainly in the absence of Lewis acid although isoxazolidine-4-carboxylates were obtained mainly in the presence of Lewis acid. When the reaction of C,N-diarylaldonitrones (1k, 1m, 1n) with ethyl acrylate was carried out in the presence of Lewis acid, the cleavage of the N-O bond of the cycloadducts giving γ-aminoalcohols was also observed besides a reverse phenomenon of regioselectivity.

Synthesis of 1,5-Diamino-1,5-dihydrobenzobistriazole (DABT) and Its Use as a 1,4-Benzadiyne Equivalent

Amination of 1,5-dihydrobenzobistriazole (9) gives the 1,5- and 1,7-diamino derivatives 3 and 10 both useful as 1,4-benzadiyne equivalents, as well as the 1,6 isomer 11 and the recyclable monoamino derivatives 12 and 13.Sixteen examples of the synthetic utility of DABT (3) with lead tetraacetate in bisannulations are described (Table 1).The aryne-trapping dienes include ester, halogen, and carbonyl functionality; often the reactions are quite regio- and stereoselective as a consequence of the stepwise nature of the annulations.