41122-41-2Relevant academic research and scientific papers
The clean synthesis and confirmatory structural characterization of new 2-amino-4,8-dihydropyrano[3,2-b]pyran-3-cyano based on Kojic acid
Aghbash, Khadijeh Ojaghi,Pesyan, Nader Noroozi,Notash, Behrouz
, p. 2059 - 2067 (2018)
Abstract: A valuable and clean method was developed for the synthesis of the group of different novel 2-amino-4,8-dihydropyrano[3,2-b]pyran-3-carbonitriles containing a 2-aminopyran moiety by using of azido kojic acid and various 2-arylidinemalononitriles in the presence of NH4Cl as a catalyst in a green solvent (ethanol) with excellent yields. All structures were analyzed by FT-IR, 1H, 13C NMR spectroscopy, and representatively, one compound was analyzed by X-ray crystallography technique. Crystallographic analyses indicated that of this compound a dimer formed via two weak intermolecular hydrogen bonds with d(N···O) distances of 2.927?? and made a 14-membered ring with centrosymmetric (Ci) form. Graphical abstract: [Figure not available: see fulltext.].
