411233-40-4

Upstream product

• 411233-39-1 2-fluoro-4-(methylsulfanyl)benzonitrile 
• 779331-21-4 trifluoromethanesulfonic acid 2-fluoro-4-(methylsulfonyl)phenyl ester 
• 557-21-1 dicyanozinc 
• 20951-14-8 2-fluoro-1-methoxy-4-(methylsulfonyl)benzene 
• 66624-36-0 2-fluoro-1-methoxy-4-(methylsulfanyl)benzene 
• 918967-37-0 2-fluoro-4-(methylsulfonyl)benzamide 

Downstream Products

• 106738-52-7 2-chloro-4-methanesulfonyl-benzylamine; hydrochloride 

Relevant academic research and scientific papers

NEW COMPOUNDS I/418

There is provided compounds of formula I, wherein R1 to R7 have meanings given in the description, which are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.

GPCR AGONISTS

Compounds of formula (I): or pharmaceutically acceptable salts thereof, are GPCR agonists and are useful as for the treatment of obesity and diabetes.

1,2,4-OXADIAZOLE DERIVATIVES AS DIPEPTIDYL PEPTIDASE-IV INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES

The present invention is directed to novel 1,2,4-oxadiazole derivatives which are inhibitors of the dipeptidyl peptidase-IV enzyme ("DP-IV inhibitors") and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.