4116-23-8 Usage
Uses
Used in Pharmaceutical Industry:
5-Dimethylaminomethyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid is used as an inhibitor for dihydroorotate dehydrogenase (DHODH) class 1A. This application is significant because DHODH is an essential enzyme in the pyrimidine biosynthesis pathway, which is crucial for the proliferation of cells, including cancer cells. By inhibiting DHODH, 5-Dimethylaminomethyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid can potentially disrupt the synthesis of pyrimidines, thereby affecting cell growth and division, particularly in cancerous cells.
The inhibition of DHODH by 5-Dimethylaminomethyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid can be employed as a targeted therapeutic approach for various types of cancer. 5-Dimethylaminomethyl-2,6-dioxo-1,2,3,6-tetrahydro-pyrimidine-4-carboxylic acid may be further developed and optimized to enhance its potency, selectivity, and pharmacokinetic properties, making it a promising candidate for the development of novel anticancer drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 4116-23-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,1 and 6 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 4116-23:
(6*4)+(5*1)+(4*1)+(3*6)+(2*2)+(1*3)=58
58 % 10 = 8
So 4116-23-8 is a valid CAS Registry Number.
