41175-03-5Relevant academic research and scientific papers
Preparation and reactions of 2-zincated 2-cyclohexen-1-one and related heterocycles
Prasad, A.S. Bhanu,Knochel, Paul
, p. 16711 - 16720 (1997)
The reaction of zinc dust in THF with 2-iodocyclohexenone 6, 3-iodo-N- benzoyl-l-azacyclohex-2-en-4-one 8 provides the corresponding zinc organometallics 3 and 4 which react in the presence of a copper(I) catalyst or palladium(O) catalyst with an allylic bromide or alkenyl and aryl iodides in satisfactory to good yields. Several of these products can further be cyclized leading diastereoselectively to a polyfunctional decaline 12 or a pyrrole derivative 13. A 6-zincated uracil reagent has also been prepared and reacted with aryl iodides in the presence of a palladium catalyst leading to new 6-arylated uracil derivatives 11.
Synthesis of 4-acetoxyindoles and related derivatives by means of air oxidation of 4-oxo-4,5,6,7-tetrahydroindoles obtained from nitroalkenes and cyclohexane-1,3-diones
Arai, Masaki,Miyauchi, Yayoi,Miyahara, Tadashi,Ishikawa, Teruhiko,Saito, Seiki
scheme or table, p. 122 - 126 (2009/05/28)
A novel method for synthesizing 4-hydroxyindole derivatives from cyclohexane-1,3-diones and nitroalkenes have been developed in which a newly developed air oxidation of 4-oxo-4,5,6,7-tetrahydroindoles is playing a crucial role. Georg Thieme Verlag Stuttga
