41192-81-8

Usage

Also known as

CF3Q

Type of compound

Fluorinated derivative of 7-quinolinol

Structural feature

Trifluoromethyl group attached to the second position of the quinolinol ring

Classification

Fluorinated arene

Uses

Ligand in organometallic chemistry, building block in the synthesis of pharmaceuticals and agrochemicals

Potential applications

Catalysis and material science

Unique properties

Structural and electronic properties

Upstream product

• 127223-93-2 (E)-4-(dimethylamino)-1,1,1-trifluorobut-3-en-2-one 
• 591-27-5 m-Hydroxyaniline 

Relevant academic research and scientific papers

Tetracyclic pyrimidinone compound, preparation method, composition and application thereof

A tetracyclic pyrimidinone compound represented by a formula (I) or a pharmaceutically acceptable salt thereof has a structure represented by a formula (I), is a brand new Lp-PLA2 inhibitor, and can be used for treating neurodegenerative related diseases such as Alzheimer's disease (AD), glaucoma, age-related macular degeneration (AMD), or cardiovascular diseases including atherosclerosis and thelike.

3-Trifloxy-3-trifluoromethylpropeniminium triflate: Reaction with aromatic amines - An efficient synthesis of 2-trifluoromethylquinolines

The reaction of iminium triflates 2 and 7 with various aromatic amines were investigated. The 2-R(f)-substituted quinolines 3 and 8 were prepared in excellent yields by the reaction of 2 and 7, respectively, with substituted anilines. The reactions of 2 a