41194-16-5 Usage
General Description
Apramycin sulfate is a broad-spectrum aminoglycoside antibiotic used in veterinary medicine to treat bacterial infections in livestock, particularly in poultry. It works by inhibiting protein synthesis in bacteria, and is effective against a wide range of gram-negative and some gram-positive bacteria. Apramycin sulfate is not FDA-approved for use in humans, but has been used off-label in some cases to treat multi-drug resistant bacterial infections. It is typically administered through injection or added to animal feed. Like other aminoglycoside antibiotics, there is a risk of nephrotoxic and ototoxic side effects with prolonged use of apramycin sulfate.
Check Digit Verification of cas no
The CAS Registry Mumber 41194-16-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,1,9 and 4 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 41194-16:
(7*4)+(6*1)+(5*1)+(4*9)+(3*4)+(2*1)+(1*6)=95
95 % 10 = 5
So 41194-16-5 is a valid CAS Registry Number.
InChI:InChI=1/C21H41N5O11.H2O4S/c1-26-11-14(30)18-8(33-20(11)37-21-16(32)13(29)10(25)9(4-27)34-21)3-7(24)19(36-18)35-17-6(23)2-5(22)12(28)15(17)31;1-5(2,3)4/h5-21,26-32H,2-4,22-25H2,1H3;(H2,1,2,3,4)/t5-,6-,7-,8-,9+,10-,11-,12-,13-,14+,15+,16+,17+,18+,19-,20+,21+;/m1./s1
41194-16-5Relevant articles and documents
NOVEL AMINOGLYCOSIDE ANTIBIOTIC EFFECTIVE AGAINST MULTIDRUG-RESISTANT BACTERIA
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Paragraph 0299; 0306; 0331; 0335, (2018/06/15)
A compound represented by the following general formula (I) or a pharmaceutically acceptable salt or solvate thereof, and a pharmaceutical composition thereof, and the use thereof to prevent or treat infectious diseases and a method to prevent or treat infectious diseases using those regimen are disclosed. The compound represented by formula (I) has an antibacterial activity against both gram-positive and gram-negative bacteria, and is useful in the prevention or treatment of infectious diseases caused by these bacteria.
Total synthesis of aminoglycoside antibiotics, apramycin and saccharocin (KA 5685)
Tatsuta,Akimoto,Takahashi,et al.
, p. 529 - 538 (2007/10/02)
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T:Toxic;
