41200-96-8Relevant academic research and scientific papers
A method for synthesizing intermediate oxadiazon
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Paragraph 0077; 0087; 0105-0110; 0126-0132; 0148-0152, (2019/07/04)
The invention discloses a method for synthesizing intermediate oxadiazon, comprises the following steps: takes amino phenol as an initial raw material; to m-aminophenol acylation reaction is carried out, thereby obtaining a reaction solution A; the reaction solution A to proceed chlorination reaction, to obtain 2, 4 - dichloro - 5 hydroxy acetanilide; to the 2, 4 - dichloro - 5 hydroxy acetanilide etherification reaction, to obtain 2, 4 - dichloro - 5 isopropoxy acetanilide; to the 2, 4 - dichloro - 5 isopropoxy acetyl aniline to deprotected, get 2, 4 - dichloro - 5 isopropoxyaniline. The invention of 2, 4 - dichloro - 5 - isopropoxy aniline synthesis method to avoid the pollution of the environment, but there are few process steps, high yield.
Oxadiazon synthesis method
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, (2017/06/02)
The invention discloses an oxadiazon synthesis method, wherein 2,4-dichloro-5-nitrophenol and 2-bromopropane are adopted as starting raw materials, and etherification, reduction, diazo reduction, acylation, light cyclization and other reaction process routes are performed to produce oxadiazon. The oxadiazon synthesis method has the following advantages that the operation process is convenient and the total yield is up to 99%; the raw materials are domestic and are easy to obtain, such that the raw material cost is easily reduced and the market competitiveness can be improved; and the solid phosgene is used to replace the hypertoxic phosgene used in the existing process, such that the reaction is stable and safe, the pollutant discharging during the production process is reduced, and the process is the environmentally friendly chemical industry process.
Solvent-free catalytic hydrogenation method for preparation of 2,4-dichloro-5-isopropoxy aniline
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Paragraph 0008; 0009; 0010; 0011; 0012, (2017/02/17)
The invention especially discloses a solvent-free method for hydrogenation preparation of 2,4-dichloro-5-isopropoxy aniline from 2,4-dichloro-5-isopropoxy nitrobenzene, belonging to the field of catalytic hydrogenation production. The method uses 2,4-dichloro-5-isopropoxy nitrobenzene as a raw material and is characterized in that 2,4-dichloro-5-isopropoxy nitrobenzene reacts with hydrogen at a temperature of 80 to 100 DEG C and a pressure of 0.3 to 2.5 MPa in the presence of a catalyst and an auxiliary agent, no solvent is added, and water is separated after completion of the reaction so as to obtain chloroaniline. The catalyst is a noble metal catalyst prepared through independent research and development, and the usage amount of the catalyst is 0.05 to 20% of the mass of 2,4-dichloro-5-isopropoxy nitrobenzene; the auxiliary agent is a mixture of ethanolamine and pyridine, and the usage amount of the auxiliary agent is 0.01 to 10% of the mass of 2,4-dichloro-5-isopropoxy nitrobenzene; and chromatographic purity of obtained 2,4-dichloro-5-isopropoxy aniline is 99.5% or above, a dechlorination amount can be controlled within 0.1%, a conversion rate is 100%, and yield is 95% or above.
Herbicidal 2-aryl-1,2,4-triazine-3,5(2H,4H)-diones and sulfur analogs thereof
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, (2008/06/13)
Herbicidal utility for 2-aryl-1,2,4-triazine-3,5(2H,4H)-diones and sulfur analogs is disclosed and exemplified. Many of the disclosed compounds are novel. Methods for preparing the herbicidal compounds and intermediates therefor are also disclosed.
