412031-49-3

Downstream Products

• 412031-53-9 Acetic acid (2R,3R,4R,6S)-4-acetoxy-2-acetoxymethyl-6-((2S,3S,4R)-3,4-bis-benzyloxy-2-docosanoylamino-octadecyloxy)-tetrahydro-pyran-3-yl ester 
• 412031-51-7 Acetic acid (2R,3S,4S,5S,6S)-3-acetoxy-2-acetoxymethyl-6-((2S,3S,4R)-2-azido-3,4-bis-benzyloxy-octadecyloxy)-5-iodo-tetrahydro-pyran-4-yl ester 
• 412031-52-8 Acetic acid (2R,3R,4R,6S)-4-acetoxy-2-acetoxymethyl-6-((2S,3S,4R)-2-amino-3,4-bis-benzyloxy-octadecyloxy)-tetrahydro-pyran-3-yl ester 
• 412031-50-6 ((2S,3S,4R)-2-Azido-3,4-bis-benzyloxy-octadecyloxy)-triisopropyl-silane 
• 202812-10-0 (2S,3S,4S)-2-azido-3,4-di-O-benzyl-octadecan-1,3,4-triol 

Relevant academic research and scientific papers

Immunomodulating glycosphingolipids: An efficient synthesis of a 2′-deoxy-α-galactosyl-GSL

A new and efficient approach to the total synthesis of 2′-deoxy-α-galactosyl glycosphingolipids was accomplished. Commercially available 3,4,6-tri-O-acetylgalactal was used as the chiral starting material for both the sugar and phytosphingosine building blocks required for the synthesis of 1-O-(2-deoxy-α-D-galactopyranosyl)-2-docosanoylamino-1,3, 4-octadecanetriol. The key step of the synthetic strategy was the stereoselective α-glycosidation of the azido precursor of sphingosine.