412041-40-8Relevant academic research and scientific papers
Borylative Radical Cyclizations of Benzo[3,4]cyclodec-3-ene-1,5-diynes and N-Heterocyclic Carbene-Boranes
Watanabe, Takashi,Hirose, Daisuke,Curran, Dennis P.,Taniguchi, Tsuyoshi
, p. 5404 - 5409 (2017)
Borylative radical cyclization of benzo[3,4]cyclodec-3-ene-1,5-diynes to provide 5-borylated 6,7,8,9-tetrahydrobenzo[a]azulenes has been developed. The experimental results suggest that the reaction proceeds by a radical chain mechanism, in which di-tert-butyl hyponitrite (TBHN) works as a good radical initiator to form boryl radicals from N-heterocyclic carbene–boranes (NHC-boranes). The present reaction is a rare model that illustrates addition of boryl radicals to alkynes.
The Bergman reaction as a synthetic tool: Advantages and restrictions
Bowles, Daniel M,Palmer, Grant J,Landis, Chad A,Scott, John L,Anthony, John E
, p. 3753 - 3760 (2007/10/03)
The Bergman cycloaromatization reaction efficiently converts easily prepared acyclic enediynes into aromatic rings. In order to prepare larger, functionalized fused aromatic systems using this reaction, a thorough understanding of how functionalization affects cycloaromatization is necessary. We present here our studies on the influence of substituents at three different functionalization sites on cycloaromatization, and how these functional groups can be tailored to prepare more complex systems.
