41208-52-0Relevant articles and documents
Rhodium catalyzed selective hydroaminomethylation of biorenewable eugenol under aqueous biphasic condition
Jagtap, Samadhan A.,Gowalkar, Shilpa P.,Monflier, Eric,Ponchel, Anne,Bhanage, Bhalchandra M.
, p. 108 - 116 (2018/04/17)
This work reports a highly regioselective hydroaminomethylation of eugenol, anethole and estragole with piperidine in aqueous medium. This catalytic system was composed of rhodium complexes stabilized by trisulfonated triphenylphosphine (TPPTS) and of a native or chemically modified cyclodextrins. Various cyclodextrins such as α-cyclodextrins (α-CD), β-cyclodextrin (β-CD), γ-cyclodextrin (γ-CD), 2-hydroxy-propyl β-cyclodextrin (hp-β-CD) and RAndomly MEthylated β-cyclodextrin (RAME-β-CD) have been tested. The effect of different parameters such as syngas pressure, time, temperature, catalyst precursor/loading and the ratio of Metal/Ligand/Cyclodextrin were also investigated. The addition of cyclodextrins as a mass transfer agent remarkably increased the rate reaction and the selectivity of linear amines, specially in the case of RAME-β-CD. So, the Rh/TPPTS/RAME-β-CD as a catalyst exhibited high conversion (92%) and selectivity (79.2%) towards the linear amine as major product under mild conditions. Finally, the catalytic system was recycled up to five times without a significant loss in activity and selectivity.
From Internal Olefins to Linear Amines: Ruthenium-Catalyzed Domino Water-Gas Shift/Hydroaminomethylation Sequence
Liu, Jie,Kubis, Christoph,Franke, Robert,Jackstell, Ralf,Beller, Matthias
, p. 907 - 912 (2016/02/18)
A selective ruthenium-catalyzed water-gas shift/hydroformylation of internal olefins and olefin mixtures is reported. This novel domino reaction takes place through a catalytic water-gas shift reaction, subsequent olefin isomerization, followed by hydrofo
Enantio- and regioselective CuH-catalyzed hydroamination of alkenes
Zhu, Shaolin,Niljianskul, Nootaree,Buchwald, Stephen L.
supporting information, p. 15746 - 15749 (2013/11/06)
A highly enantio- and regioselective copper-catalyzed hydroamination reaction of alkenes has been developed using diethoxymethylsilane and esters of hydroxylamines. The process tolerates a wide variety of substituted styrenes, including trans-, cis-, and β,β-disubstituted styrenes, to yield α-branched amines. In addition, aliphatic alkenes coupled to generate exclusively the anti-Markovnikov hydroamination products.
