4121-67-9 Usage
Uses
Used in Neurodegenerative Disease Research:
Thioflavin T is employed as a research tool for studying neurodegenerative diseases, particularly those associated with amyloid fibrils such as Alzheimer's and Parkinson's. Its selective binding to these protein aggregates allows for the visualization and analysis of the disease's progression and the evaluation of potential therapeutic interventions.
Used in Diagnostic Assays:
In the development of diagnostic assays, Thioflavin T serves as a key component for the detection and quantification of amyloid fibrils. Its fluorescence properties upon binding to these aggregates facilitate the sensitive and specific identification of disease markers, contributing to the early diagnosis and monitoring of neurodegenerative conditions.
Used in Drug Screening:
Thioflavin T is utilized in drug screening methods to identify and evaluate potential therapeutic agents targeting amyloid fibrils. Its ability to bind selectively to these protein aggregates enables the assessment of drug candidates' efficacy in preventing or disrupting the formation of amyloid structures, which is crucial for the development of novel treatments for neurodegenerative diseases.
Used in Biomedical Imaging:
In the field of biomedical imaging, Thioflavin T is applied as a fluorescent probe for the in vivo visualization of amyloid deposits. Its selective binding and fluorescence properties allow for the non-invasive detection and monitoring of disease progression, providing valuable insights into the pathophysiology of neurodegenerative disorders and the effectiveness of therapeutic interventions.
Used in Chemical Research:
Beyond its applications in biology and medicine, Thioflavin T is also employed in chemical research for studying the formation and properties of amyloid fibrils. Its interaction with these protein aggregates provides insights into the molecular mechanisms underlying their formation and stability, contributing to a deeper understanding of the factors influencing protein aggregation and its implications in various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 4121-67-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,1,2 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4121-67:
(6*4)+(5*1)+(4*2)+(3*1)+(2*6)+(1*7)=59
59 % 10 = 9
So 4121-67-9 is a valid CAS Registry Number.
InChI:InChI=1/C26H16N2O5S2.Na/c1-13-6-9-20-24(25(13)35(31,32)33)34-26(28-20)15-8-10-18-14(12-15)7-11-19(27-18)21-22(29)16-4-2-3-5-17(16)23(21)30;/h2-12,21H,1H3,(H,31,32,33);/q;+1/p-1
