412293-40-4

Usage

Uses

Used in Pharmaceutical Industry:
(R)-3-(2-chloroacetyl)thiazolidine-4-carbonitrile is used as an intermediate in the synthesis of various drugs for its unique structural features and reactivity. Its ability to form different chemical bonds makes it a valuable component in the development of new pharmaceutical compounds.
Used in Antimicrobial Applications:
In the field of antimicrobial research, (R)-3-(2-chloroacetyl)thiazolidine-4-carbonitrile is used as an active ingredient for its antimicrobial properties. Its potential to inhibit the growth of harmful microorganisms makes it a promising candidate for the development of new therapeutic agents to combat bacterial and fungal infections.
Used in Antifungal Applications:
Similarly, (R)-3-(2-chloroacetyl)thiazolidine-4-carbonitrile is used as an antifungal agent due to its ability to exhibit antifungal properties. This characteristic positions the compound as a potential candidate for the development of new antifungal drugs, addressing the growing need for novel treatments against fungal infections.

Upstream product

• 637018-75-8 (4R)-3-(chloroacetyl)-1,3-thiazolidine-4-carboxamide 

Relevant academic research and scientific papers

NOVEL DIPEPTIDYL PEPTIDASE INHIBITORS AND PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The present invention relates to novel compounds representated by formula (I), where R, R1, R2, R3, X, Y, m, n are as defined.The present invention relates to compounds of the general formula I their derivatives, their analogs, their tautomeric forms, their stereoisomers, their diastereomers, their bioisosteres, their polymorphs, their pharmaceutically acceptable salts and pharmaceutically acceptable compositions containing them which are predominantly dipeptidyl peptidase IV inhibitors. The present invention also relates to the processes for the preparation of novel compounds of formula (I) and their use in treating type II diabetes and diabetic complications thereof and also for treating dislipidemia, hypercholesterolemia, obesity and hyperglycemia.

NITROGENOUS FIVE-MEMBERED RING COMPOUNDS

The present invention is to provide an aliphatic nitrogen-containing 5-membered ring compound represented by the formula [I] : wherein symbols in the formula have the following meanings;A: -CH2- or -S-,B: CH or N,R1: H, a lower alkyl group, etc.,X: a single bonding arm, -CO-, -Alk-CO-, -COCH2-, -Alk-O-, -O-CH2-, -SO2-, -S-, -COO-, -CON(R3)-, -Alk-CON(R3)-, -CON(R3)CH2-, -NHCH2-, etc.,R3: hydrogen atom or a lower alkyl group,Alk: a lower alkylene group, andR2: (1) a cyclic group which may be substituted, (2) a substituted amino group, etc., provided that when X is -CO-, then B is N, or a pharmaceutically acceptable salt thereof.

NEW COMPOUNDS

The present invention relates to the novel compounds of the general formula (I) possessing DPP-IV inhibitory activity. These compounds contain tropane building blocks.