412293-42-6

Usage

Uses

Used in Organic Synthesis:
8-Methyl-1,4-dioxaspiro[4.5]decane-8-carboxylic acid is used as a building block in organic synthesis for the development of new compounds.
Used in Pharmaceutical Research:
8-Methyl-1,4-dioxaspiro[4.5]decane-8-carboxylic acid is used as a building block in pharmaceutical research for the development of new drugs. Its unique spiro ring structure gives it potential applications in the field of medicinal chemistry.

Upstream product

• 87787-08-4 methyl 4,4-ethylenedioxy-1-methylcyclohexanecarboxylate 
• 26845-47-6 methyl 1,4-dioxaspiro[4.5]decane-8-carboxylate 
• 6297-22-9 4-carbomethoxycyclohexanone 
• 17159-79-4 ethyl 4-oxocyclohexane-1-carboxylate 
• 1489-97-0 ethyl 1,4-dioxaspiro[4.5]decane-8-carboxylate 
• 24730-88-9 ethyl 8-methyl-1,4-dioxa-spiro[4.5]decane-8-carboxylate 
• 1523-89-3 methyl 1-methyl-4-oxo-2-cyclohexene-1-carboxylate 
• 37480-41-4 methyl 1-methyl-4-oxo-1-cyclohexanecarboxylate 
• 107-21-1 ethylene glycol 

Downstream Products

• 886615-91-4 (8-methyl-1,4-dioxa-spiro[4,5]dec-8-yl)-carbamic acid benzyl ester 
• 24463-41-0 1-methyl-4-oxo-cyclohexanecarboxylic acid 
• 37480-40-3 methyl 4,4-dimethoxy-1-methylcyclohexanecarboxylate 
• 1557232-69-5 (6S)-N-(1-benzyl-1H-pyrazol-4-yl)-6-(hydroxymethyl)-6-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide 
• 1557232-67-3 (6R)-N-(1-benzyl-1H-pyrazol-4-yl)-6-(hydroxymethyl)-6-methyl-4,5,6,7-tetrahydro-1H-indazole-3-carboxamide 
• 1557249-05-4 C₃₂H₅₁N₅O₃Si₂ 
• 24730-90-3 4-(hydroxymethyl)-4-methylcyclohexanone 
• 1557246-64-6 (4,4-dimethoxy-1-methylcyclohexyl)methanol 
• 1207111-50-9 4-((tert-butyldimethylsilyloxy)methyl)-4-methylcyclohexanone 
• 87787-08-4 methyl 4,4-ethylenedioxy-1-methylcyclohexanecarboxylate 
• 87787-16-4 4-(4,4-ethylenedioxy-1-methylcyclohexylmethoxy)nitrobenzene 
• 87787-22-2 4-(8-Methyl-1,4-dioxa-spiro[4.5]dec-8-ylmethoxy)-phenylamine 

Relevant academic research and scientific papers

2,3-DIHYDRO-1H-PYRROLIZINE-7-FORMAMIDE DERIVATIVE AND APPLICATION THEREOF

The present application relates to a 2,3-dihydro-1H-pyrrolizine-7-formamide derivative as a nucleoprotein inhibitor and a use in preparation of a drug for treating HBV related diseases. The present application specifically relates to a compound represented by formula (II), and isomers or pharmaceutically acceptable salts thereof.

4,5,6-TRI-SUBSTITUTED INDAZOLES DERIVATIVES, PREPARATION THEREOF, AND USE THEREOF IN MEDICINES

Provided are 4,5,6-tri-substituted indazoles derivatives, a preparation method therefor, and a use thereof in medicines. Specifically, provided are compounds of formula (I) or pharmaceutically acceptable salts, stereoisomers, solvates, or prodrugs thereof

PYRAZOLYLAMINOBENZIMIDAZOLE DERIVATIVES AS JAK INHIBITORS

The present invention provides compounds of the formula below (I'): where R, and R1-R3 are as described herein, methods of treating patients for certain types of autoimmune diseases and cancer, and processes for preparing the compounds.

2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS

A compound of the formula (I) or a pharmaceutically acceptable salt thereof: [wherein X is CFH, or CF?2#191, R?1? is the moiety represented by the formula: [wherein R?2? is (lower) alkyl, R?3? is phenyl-(lower)alkyl, and the like.], and the like.] Compounds of formula (I) inhibit DPP-IV activity. They are therefore useful in the treatment of conditions mediated by DPP-IV, such as NIDDM.

NITROGENOUS FIVE-MEMBERED RING COMPOUNDS

The present invention is to provide an aliphatic nitrogen-containing 5-membered ring compound represented by the formula [I] : wherein symbols in the formula have the following meanings;A: -CH2- or -S-,B: CH or N,R1: H, a lower alkyl group, etc.,X: a single bonding arm, -CO-, -Alk-CO-, -COCH2-, -Alk-O-, -O-CH2-, -SO2-, -S-, -COO-, -CON(R3)-, -Alk-CON(R3)-, -CON(R3)CH2-, -NHCH2-, etc.,R3: hydrogen atom or a lower alkyl group,Alk: a lower alkylene group, andR2: (1) a cyclic group which may be substituted, (2) a substituted amino group, etc., provided that when X is -CO-, then B is N, or a pharmaceutically acceptable salt thereof.