412317-95-4Relevant articles and documents
Synthesis of novel paclitaxel prodrugs designed for bioreductive activation in hypoxic tumour tissue
Damen, Eric W.P.,Nevalainen, Tapio J.,Van den Bergh, Toine J.M.,De Groot, Franciscus M.H.,Scheeren, Hans W.
, p. 71 - 77 (2002)
The syntheses and preliminary evaluation of the first potential bioreductive paclitaxel prodrugs are described. These prodrugs were designed as potential candidates in more selective chemotherapy by targeting hypoxic tumour tissue. Aromatic nitro and azid