41273-34-1Relevant articles and documents
Methods for synthesis of carotenoids, including analogs, derivatives, and synthetic and biological intermediates
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Page/Page column 42; 17, (2008/12/08)
A method for synthesizing intermediates for use in the synthesis of carotenoid synthetic intermediates, carotenoid analogs, and/or carotenoid derivatives. The carotenoid analog, derivative, or intermediate may be administered to a subject for the inhibition and/or amelioration of any disease that involves production of reactive oxygen species, reactive nitrogen species, radicals and/or non-radicals. In some embodiments, the invention may include methods for synthesizing chemical compounds including an analog or derivative of a carotenoid. Carotenoid analogs or derivatives may include acyclic end groups. In some embodiments, a carotenoid analog or derivative may include at least one substituent. The substituent may enhance the solubility of the carotenoid analog or derivative such that the carotenoid analog or derivative at least partially dissolves in water.
SYNTHESIS AND PURIFICATION OF THE ALLOFARNESENES
Williams, Howard J.,Strand, Michael R.,Vinson, S. Bradleigh
, p. 2763 - 2767 (2007/10/02)
The eight isomers of allofarnesene (3,7,11-trimethyl-2,4,6,10-dodecatetraene) were prepared using Wittig reactions.The four E-4 isomers could be separated using GC but the unstable Z-4 isomers required HPLC on silver nitrate impregnated silica gel for analysis.Purified samples of each isomer were prepared for spectral studies.The configuration of the pseudoionone (6,10-dimethyl-3,5,9-undecatriene-2-one) starting materials was also studied, confirming previous results.
