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5-IODOPHTHALIDE is a chemical compound with the molecular formula C8H5IO2. It is a yellow solid that is commonly used in organic synthesis and pharmaceutical research. As a derivative of phthalic anhydride, 5-Iodophthalide is known for its unique and valuable properties, such as its ability to act as a precursor for various pharmaceutical intermediates. It is also used as a building block in the synthesis of biologically active compounds and has potential applications in the development of new drugs. Furthermore, 5-Iodophthalide is a valuable reagent for the synthesis of complex organic molecules, making it an important and versatile chemical in the field of organic chemistry.

41284-92-8

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41284-92-8 Usage

Uses

Used in Pharmaceutical Research:
5-IODOPHTHALIDE is used as a precursor for various pharmaceutical intermediates, contributing to the development of new drugs and therapeutic agents.
Used in Organic Synthesis:
5-IODOPHTHALIDE is used as a building block in the synthesis of biologically active compounds, playing a crucial role in creating complex organic molecules for various applications.
Used in Chemical Research:
5-IODOPHTHALIDE is utilized as a valuable reagent in the field of organic chemistry, aiding in the synthesis of intricate organic molecules and advancing scientific understanding of chemical reactions and processes.

Check Digit Verification of cas no

The CAS Registry Mumber 41284-92-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,1,2,8 and 4 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 41284-92:
(7*4)+(6*1)+(5*2)+(4*8)+(3*4)+(2*9)+(1*2)=108
108 % 10 = 8
So 41284-92-8 is a valid CAS Registry Number.

41284-92-8Relevant academic research and scientific papers

Diarylthiophenes as inhibitors of the pore-forming protein perforin

Miller, Christian K.,Huttunen, Kristiina M.,Denny, William A.,Jaiswal, Jagdish K.,Ciccone, Annette,Browne, Kylie A.,Trapani, Joseph A.,Spicer, Julie A.

, p. 355 - 360 (2016/01/09)

Evolution from a furan-containing high-throughput screen (HTS) hit (1) resulted in isobenzofuran-1(3H)-one (2) as a potent inhibitor of the function of both isolated perforin protein and perforin delivered in situ by intact KHYG-1 NK cells. In the current study, structure-activity relationship (SAR) development towards a novel series of diarylthiophene analogues has continued through the use of substituted-benzene and -pyridyl moieties as bioisosteres for 2-thioxoimidazolidin-4-one (A) on a thiophene (B) -isobenzofuranone (C) scaffold. The resulting compounds were tested for their ability to inhibit perforin lytic activity in vitro. Carboxamide (23) shows a 4-fold increase(2) in lytic activity against isolated perforin and provides good rationale for continued development within this class.

PROCESSES FOR THE PREPARATION OF CITALOPRAM AND ITS INTERMEDIATE 5-AMINOPHTHALIDE

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Page/Page column 9, (2010/11/24)

The invention relates to processes for the preparation of 5-amino-2-benzofuran- l(3H)-one of Formula (I), and to the use of this compound as an intermediate for the preparation of citalopram. The invention also relates to a process for the preparation of citalopram or a salt thereof, and pharmaceutical compositions that include the citalopram or a salt thereof.

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